Table 1

Immunohistologic analysis of PTP1B protein expression in hematolymphoid neoplasia

Lymphoma subtypeTotal positive*% positive
B-cell lymphoma (N = 339)   
Follicular lymphoma   
    Grade 1 0/48 
    Grade 2 8/59 14 
    Grade 3 20/68 29 
Diffuse large B-cell lymphoma 46/80 58 
Burkitt lymphoma 0/4 
Marginal zone lymphoma 7/21 33 
Mantle cell lymphoma 3/18 17 
Small lymphocytic lymphoma/CLL 2/32 
Precursor B-lymphoblastic lymphoma 1/7 14 
Plasma cell neoplasms 0/2 
T-cell lymphoma (N = 35)   
    Precursor T-lymphoblastic lymphoma 0/11 
    Peripheral T-cell lymphoma 10/16 62 
    Anaplastic large cell lymphoma 1/5 20 
    NK lymphoma 0/3 
Histiocytic neoplasms (N = 7)   
    Langerhan cell histiocytosis 3/4 75 
    Rosai-Dorfman disease 3/3 100 
Lymphoma subtypeTotal positive*% positive
B-cell lymphoma (N = 339)   
Follicular lymphoma   
    Grade 1 0/48 
    Grade 2 8/59 14 
    Grade 3 20/68 29 
Diffuse large B-cell lymphoma 46/80 58 
Burkitt lymphoma 0/4 
Marginal zone lymphoma 7/21 33 
Mantle cell lymphoma 3/18 17 
Small lymphocytic lymphoma/CLL 2/32 
Precursor B-lymphoblastic lymphoma 1/7 14 
Plasma cell neoplasms 0/2 
T-cell lymphoma (N = 35)   
    Precursor T-lymphoblastic lymphoma 0/11 
    Peripheral T-cell lymphoma 10/16 62 
    Anaplastic large cell lymphoma 1/5 20 
    NK lymphoma 0/3 
Histiocytic neoplasms (N = 7)   
    Langerhan cell histiocytosis 3/4 75 
    Rosai-Dorfman disease 3/3 100 
*

Cases were scored positive if more than 30% of lymphoma cells stained for PTP1B.

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