HJV polymorphisms and iron values
| Location/Dx . | Genotype (no.) . | Tf saturation, % . | TIBC, μM . | Serum ferritin, μg/L . |
|---|---|---|---|---|
| Intron 2 144126630 | ||||
| hh | C/G (3) | 96.5 ± 0.5 | 31.4 ± 12.0 | 1733.0 ± 1222.0 |
| C/C (75) | 86.4 ± 1.8 | 48.0 ± 1.2 | 1500.0 ± 162.4 | |
| PCT | C/G (9) | 47.6 ± 11.9 | 58.8 ± 6.9 | 298.2 ± 137.7 |
| C/C (79) | 45.8 ± 3.7 | 59.9 ± 2.3 | 468.1 ± 83.5 | |
| Intron 3 144127413 | ||||
| hh | C/T (8) | 91.9 ± 3.0 | 46.3 ± 4.8 | 2677.4 ± 534.6 |
| C/C (70) | 86.2 ± 2.0 | 46.9 ± 1.2 | 1360.5 ± 147.5 | |
| PCT | C/T (9) | 42.0 ± 7.5 | 56.2 ± 6.6 | 462.7 ± 319.8 |
| C/C (74) | 42.8 ± 4.0 | 60.8 ± 2.3 | 395.4 ± 76.5 | |
| 3′ flank 144129018 | ||||
| hh | T/C (8) | 92.0 ± 3.0 | 46.3 ± 4.8 | 2677.4 ± 534.6 |
| T/T (75) | 86.2 ± 1.9 | 47.5 ± 1.2 | 1535.0 ± 200.6 | |
| PCT | T/C (9) | 52.7 ± 7.3 | 51.8 ± 4.8 | 552.1 ± 239.7 |
| T/T (77) | 45.1 ± 4.2 | 61.0 ± 2.4 | 406.3 ± 77.8 |
| Location/Dx . | Genotype (no.) . | Tf saturation, % . | TIBC, μM . | Serum ferritin, μg/L . |
|---|---|---|---|---|
| Intron 2 144126630 | ||||
| hh | C/G (3) | 96.5 ± 0.5 | 31.4 ± 12.0 | 1733.0 ± 1222.0 |
| C/C (75) | 86.4 ± 1.8 | 48.0 ± 1.2 | 1500.0 ± 162.4 | |
| PCT | C/G (9) | 47.6 ± 11.9 | 58.8 ± 6.9 | 298.2 ± 137.7 |
| C/C (79) | 45.8 ± 3.7 | 59.9 ± 2.3 | 468.1 ± 83.5 | |
| Intron 3 144127413 | ||||
| hh | C/T (8) | 91.9 ± 3.0 | 46.3 ± 4.8 | 2677.4 ± 534.6 |
| C/C (70) | 86.2 ± 2.0 | 46.9 ± 1.2 | 1360.5 ± 147.5 | |
| PCT | C/T (9) | 42.0 ± 7.5 | 56.2 ± 6.6 | 462.7 ± 319.8 |
| C/C (74) | 42.8 ± 4.0 | 60.8 ± 2.3 | 395.4 ± 76.5 | |
| 3′ flank 144129018 | ||||
| hh | T/C (8) | 92.0 ± 3.0 | 46.3 ± 4.8 | 2677.4 ± 534.6 |
| T/T (75) | 86.2 ± 1.9 | 47.5 ± 1.2 | 1535.0 ± 200.6 | |
| PCT | T/C (9) | 52.7 ± 7.3 | 51.8 ± 4.8 | 552.1 ± 239.7 |
| T/T (77) | 45.1 ± 4.2 | 61.0 ± 2.4 | 406.3 ± 77.8 |
Dx indicates diagnosis; and TIBC, total iron binding capacity.
Numbers in bold represent values statistically different from the most common haplotype (P < .001 by independent sample t test. 95% confidence intervals do not overlap). Numbers in the “Location” column represent the UCSC genome browser designations.