Table 1 Leukocytosis develops in FLT3... | American Society of Hematology

Table 1

Leukocytosis develops in FLT3^wt/ITD mice

Parameter/Age, mo	Wild-type	FLT3^wt/ITD
WBC, × 10⁹/L
2	12.5 ± 5.0	7.9 ± 3.5
12	11.9 ± 5.4	23.0 ± 8.4*
RBC, × 10¹²/L
2	9.4 ± 0.4	8.5 ± 0.8
12	9.3 ± 0.6	6.9 ± 1.7*
Hemoglobin, g/L
2	146 ± 6	136 ± 10
12	146 ± 10	111 ± 25*
Platelets, × 10⁹/L
2	747.6 ± 129.2	660.9 ± 172.3
12	704.6 ± 118.1	560.8 ± 208.2
Neutrophils, × 10⁹/L
2	1.8 ± 1.4	1.2 ± 1.0
12	3.1 ± 2.2	6.1 ± 6.5
Monocytes, × 10⁹/L
2	0.5 ± 0.1	0.6 ± 0.3
12	0.8 ± 0.5	5.8 ± 7.1
Lymphocytes, × 10⁹/L
2	9.7 ± 2.1	4.0 ± 1.5*
12	7.4 ± 2.5	10.8 ± 8.6
Eosinophils, × 10⁹/L
2	0.28 ± 0.39	0.08 ± 0.08
12	0.52 ± 0.32	0.31 ± 0.32
Basophils, × 10⁹/L
2	0.08 ± 0.03	0.02 ± 0.02
12	0.14 ± 0.08	0.06 ± 0.08

Parameter/Age, mo	Wild-type	FLT3^wt/ITD
WBC, × 10⁹/L
2	12.5 ± 5.0	7.9 ± 3.5
12	11.9 ± 5.4	23.0 ± 8.4*
RBC, × 10¹²/L
2	9.4 ± 0.4	8.5 ± 0.8
12	9.3 ± 0.6	6.9 ± 1.7*
Hemoglobin, g/L
2	146 ± 6	136 ± 10
12	146 ± 10	111 ± 25*
Platelets, × 10⁹/L
2	747.6 ± 129.2	660.9 ± 172.3
12	704.6 ± 118.1	560.8 ± 208.2
Neutrophils, × 10⁹/L
2	1.8 ± 1.4	1.2 ± 1.0
12	3.1 ± 2.2	6.1 ± 6.5
Monocytes, × 10⁹/L
2	0.5 ± 0.1	0.6 ± 0.3
12	0.8 ± 0.5	5.8 ± 7.1
Lymphocytes, × 10⁹/L
2	9.7 ± 2.1	4.0 ± 1.5*
12	7.4 ± 2.5	10.8 ± 8.6
Eosinophils, × 10⁹/L
2	0.28 ± 0.39	0.08 ± 0.08
12	0.52 ± 0.32	0.31 ± 0.32
Basophils, × 10⁹/L
2	0.08 ± 0.03	0.02 ± 0.02
12	0.14 ± 0.08	0.06 ± 0.08

A total of 50 μL peripheral blood cells were collected from mouse retrooccular vessels and subjected to complete blood cell counting and WBC differential counting. Statistical analysis was performed based on data from 10 mice in each group. Data are means plus or minus SD.

P < .05.

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