Table 1

Summary of antitumor effect generated by αGC-loaded A20 vaccination

Vaccination modelSurvival rate, no. (%)
First tumor challengeSecond tumor challenge
Prophylactic   
    Nil 0/20 (0) 0/14 (0) 
    A20/veh 0/19 (0) — 
    A20/αGC 19/19 (100) 19/19 (100) 
Therapeutic, day =5   
    Nil 0/15 (0) 0/10 (0) 
    A20/veh 0/16 (0) — 
    A20/αGC 7/16 (44) 7/7 (100) 
Therapeutic, day =10   
    Nil 0/10 (0) ND 
    A20/veh 0/10 (0) ND 
    A20/αGC 2/10 (20) ND 
Vaccination modelSurvival rate, no. (%)
First tumor challengeSecond tumor challenge
Prophylactic   
    Nil 0/20 (0) 0/14 (0) 
    A20/veh 0/19 (0) — 
    A20/αGC 19/19 (100) 19/19 (100) 
Therapeutic, day =5   
    Nil 0/15 (0) 0/10 (0) 
    A20/veh 0/16 (0) — 
    A20/αGC 7/16 (44) 7/7 (100) 
Therapeutic, day =10   
    Nil 0/10 (0) ND 
    A20/veh 0/10 (0) ND 
    A20/αGC 2/10 (20) ND 

Data are pooled from 3 prophylactic and 3 therapeutic experiments.

ND indicates not determined; —, not applicable.

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