Table 2

SNPs associated with follicular lymphoma survival from phase 1 of the analysis (P ≤ 0.15 from the codominant model)

GeneSNPP value*Deleterious genotype(s)HR95% CI
FCGR2A rs1801274 .04 GG 1.63 0.90-2.94 
IL1RN rs454078 .03 AA 1.93 1.11-3.34 
IL2 rs2069762 .01 GT/TT 1.80 1.06-3.05 
IL3 rs40401 .13 CC/CT 1.28 0.77-2.13 
IL5 rs2069818 .005 AC/AA 5.58 1.66-18.6 
IL8 rs4073 .06 TT 2.14 1.26-3.63 
IL8 rs2227307 .11 TT 1.90 1.12-3.22 
IL8 rs2227306 .07 CC 1.96 1.07-3.28 
IL8RB rs1126580 .07 AA 1.64 0.97-2.79 
IL12B rs3212227 .0009 AC/CC 1.83 1.09-3.06 
IL13 rs1800925 .03 CT/TT 1.56 0.92-2.66 
IL16 rs11325 .07 CT/TT 1.61 0.96-2.70 
TNF rs361525 .15 AG/AA 1.77 0.86-3.64 
TNF rs1799724 .09 CC 1.39 0.68-2.86 
GeneSNPP value*Deleterious genotype(s)HR95% CI
FCGR2A rs1801274 .04 GG 1.63 0.90-2.94 
IL1RN rs454078 .03 AA 1.93 1.11-3.34 
IL2 rs2069762 .01 GT/TT 1.80 1.06-3.05 
IL3 rs40401 .13 CC/CT 1.28 0.77-2.13 
IL5 rs2069818 .005 AC/AA 5.58 1.66-18.6 
IL8 rs4073 .06 TT 2.14 1.26-3.63 
IL8 rs2227307 .11 TT 1.90 1.12-3.22 
IL8 rs2227306 .07 CC 1.96 1.07-3.28 
IL8RB rs1126580 .07 AA 1.64 0.97-2.79 
IL12B rs3212227 .0009 AC/CC 1.83 1.09-3.06 
IL13 rs1800925 .03 CT/TT 1.56 0.92-2.66 
IL16 rs11325 .07 CT/TT 1.61 0.96-2.70 
TNF rs361525 .15 AG/AA 1.77 0.86-3.64 
TNF rs1799724 .09 CC 1.39 0.68-2.86 
*

P value from the trend test (codominant model) from Table S1.

SNPs recoded as 0 = low risk genotype(s) and 1 = deleterious genotype(s) based on results from Table S1.

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