Stromal cells alone or CD35+B220+ cells alone were intradermally injected into naive mice
| Inducer, × 104 cells . | Stromal cells, × 105 cells . | Day after injection . | Follicle formation . |
|---|---|---|---|
| Naive CD35+B220+ | Adult spleen P1, day 3 | 8 | + |
| None | Adult spleen P1, day 3 | 8 | NI |
| Naive CD35+B220+ | Fetal brain P3, day 12 | 14 | + |
| None | Fetal brain P3, day 12 | 14 | NI |
| Naive CD35+B220+ | None | 14 | NI |
| Naive CD35+B220+ | TEL-2 | 20 | + |
| None | TEL-2 | 20 | NI |
| Inducer, × 104 cells . | Stromal cells, × 105 cells . | Day after injection . | Follicle formation . |
|---|---|---|---|
| Naive CD35+B220+ | Adult spleen P1, day 3 | 8 | + |
| None | Adult spleen P1, day 3 | 8 | NI |
| Naive CD35+B220+ | Fetal brain P3, day 12 | 14 | + |
| None | Fetal brain P3, day 12 | 14 | NI |
| Naive CD35+B220+ | None | 14 | NI |
| Naive CD35+B220+ | TEL-2 | 20 | + |
| None | TEL-2 | 20 | NI |
Procedure is described in “Materials and methods.”
NI indicates that no lymphoid-node–like structure was found; P, number of the cell passage before used in this experiment; day, day after separation of stromal cells from each tissue.