Phenotypic analysis of pDCs, mDC subsets, and CD34+ progenitor cells: summary of data from 10 donors
| Markers . | pDC . | CD16 . | CD1c . | BDCA-3 . | CD34 . |
|---|---|---|---|---|---|
| Lineage markers | |||||
| CD3 | − | − | − | − | − |
| CD14 | − | − | − | − | − |
| CD19 | − | − | − | − | − |
| CD20 | − | − | − | − | − |
| CD21/CR2 binds C3d | − | − | − | − | − |
| CD56 | − | − | − | − | − |
| Integrins and adhesion molecules | |||||
| CD11a/LFA-1/integrin alphaL subunit | + | + | + | + | +* |
| CD11b/integrin alphaM subunit | − | + | + | − | − |
| CD11c/integrin alphaX subunit | − | + | + | + | − |
| CD50/ICAM-3 | + | + | + | + | + |
| CD54/ICAM-1 | + | + | + | + | − |
| CD2/LFA-2 | + | + | + | − | − |
| CD58/LFA-3 | + | + | + | + | + |
| CD85j/ILT2/LIR-1 | + | + | + | + | + |
| Co-stimulatory molecules | |||||
| CD80 | − | − | − | − | − |
| CD86 | +* | + | + | + | − |
| CD40 | − | − | − | − | − |
| CD83 | − | − | − | − | − |
| 4-IBB/Cdw137L | − | − | − | − | − |
| CD209/DC-SIGN | − | − | − | − | − |
| Non classical antigen presenting molecules | |||||
| CD1a | − | − | − | − | − |
| CD1b | + | + | + | + | + |
| Other molecules | |||||
| CD13 | − | + | + | + | −* |
| CD89/FcαR for IgA1 and IgA2 | − | − | − | − | − |
| CD206/Macrophage Mannose Receptor | − | − | − | − | − |
| CD207/Langerin | − | − | − | − | − |
| CD95/Fas | − | + | + | + | −* |
| CD178/FasL | − | − | − | − | − |
| TNFR I | − | − | − | − | − |
| TNFR II | +* | + | + | + | + |
| CD123/IL-3 | + | + | + | + | + |
| TNF-α | − | − | − | − | − |
| Markers . | pDC . | CD16 . | CD1c . | BDCA-3 . | CD34 . |
|---|---|---|---|---|---|
| Lineage markers | |||||
| CD3 | − | − | − | − | − |
| CD14 | − | − | − | − | − |
| CD19 | − | − | − | − | − |
| CD20 | − | − | − | − | − |
| CD21/CR2 binds C3d | − | − | − | − | − |
| CD56 | − | − | − | − | − |
| Integrins and adhesion molecules | |||||
| CD11a/LFA-1/integrin alphaL subunit | + | + | + | + | +* |
| CD11b/integrin alphaM subunit | − | + | + | − | − |
| CD11c/integrin alphaX subunit | − | + | + | + | − |
| CD50/ICAM-3 | + | + | + | + | + |
| CD54/ICAM-1 | + | + | + | + | − |
| CD2/LFA-2 | + | + | + | − | − |
| CD58/LFA-3 | + | + | + | + | + |
| CD85j/ILT2/LIR-1 | + | + | + | + | + |
| Co-stimulatory molecules | |||||
| CD80 | − | − | − | − | − |
| CD86 | +* | + | + | + | − |
| CD40 | − | − | − | − | − |
| CD83 | − | − | − | − | − |
| 4-IBB/Cdw137L | − | − | − | − | − |
| CD209/DC-SIGN | − | − | − | − | − |
| Non classical antigen presenting molecules | |||||
| CD1a | − | − | − | − | − |
| CD1b | + | + | + | + | + |
| Other molecules | |||||
| CD13 | − | + | + | + | −* |
| CD89/FcαR for IgA1 and IgA2 | − | − | − | − | − |
| CD206/Macrophage Mannose Receptor | − | − | − | − | − |
| CD207/Langerin | − | − | − | − | − |
| CD95/Fas | − | + | + | + | −* |
| CD178/FasL | − | − | − | − | − |
| TNFR I | − | − | − | − | − |
| TNFR II | +* | + | + | + | + |
| CD123/IL-3 | + | + | + | + | + |
| TNF-α | − | − | − | − | − |
– indicates negative; +, positive.
Indicates marginal positive expression.