Table 2

Circulating serum proteasome levels in healthy donors and patients with MGUS, SMM, or active MM

Healthy donorsMGUSTotal MMSmoldering MMActive MM
50 20 141 40 101 
cProteasome level      
    Median, ng/mL 224.05 378.10 599.60 314.65 744.30 
    Range, ng/mL 102.5-391.70 183.70-716.40 108.50-5181.60 108.50-1252.60 193.40-5181.60 
Healthy donorsMGUSTotal MMSmoldering MMActive MM
50 20 141 40 101 
cProteasome level      
    Median, ng/mL 224.05 378.10 599.60 314.65 744.30 
    Range, ng/mL 102.5-391.70 183.70-716.40 108.50-5181.60 108.50-1252.60 193.40-5181.60 

P values between healthy donors and patients with MGUS, between healthy donors and total patients with MM, and between SMM and AMM were less than .001. The P value between patients with MGUS and the total patients with MM was .033.

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