Table 5

Genes overexpressed in CD30+ PTCL-u compared to CD30 PTCL-u

Gene symbolGene titleFold difference of geometric means
Transferases   
    MGST3 Microsomal glutathione S-transferase 3 0.39 
    NANS N-acetylneuraminic acid synthase (sialic acid synthase) 0.48 
    NAGA N-acetylgalactosaminidase, alpha 0.54 
    CDS1 CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1 0.56 
    FNTB Famesyltransferase, CAAX box, beta 0.61 
    BCKDK Branched chain ketoacid dehydrogenase kinase 0.64 
    TGM6 Transglutaminase 6 0.76 
    PDPK1 3-Phosphoinositide dependent protein kinase-1 0.84 
Transcription   
    SNFT Jun dimerization protein p21SNFT 0.13 
    IMP-3 IGF-II mRNA-binding protein 3 0.2 
    PAX8 Paired box gene 8 0.72 
    BCORL1 BCL6 corepressor-like 1 0.76 
    GATA1 GATA binding protein 1 (globin transcription factor 1) 0.77 
Cell adhesion   
    CEECAM1 Cerebral endothelial cell adhesion molecule 1 0.68 
    MADCAM1 Mucosal vascular addressin cell adhesion molecule 1 0.83 
Oncogene   
    RAB17 RAB17, member RAS oncogene family 0.78 
    RAB35 RAB35, member RAS oncogene family 0.85 
    RHOD Ras homolog gene family, member D 0.74 
Gene symbolGene titleFold difference of geometric means
Transferases   
    MGST3 Microsomal glutathione S-transferase 3 0.39 
    NANS N-acetylneuraminic acid synthase (sialic acid synthase) 0.48 
    NAGA N-acetylgalactosaminidase, alpha 0.54 
    CDS1 CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1 0.56 
    FNTB Famesyltransferase, CAAX box, beta 0.61 
    BCKDK Branched chain ketoacid dehydrogenase kinase 0.64 
    TGM6 Transglutaminase 6 0.76 
    PDPK1 3-Phosphoinositide dependent protein kinase-1 0.84 
Transcription   
    SNFT Jun dimerization protein p21SNFT 0.13 
    IMP-3 IGF-II mRNA-binding protein 3 0.2 
    PAX8 Paired box gene 8 0.72 
    BCORL1 BCL6 corepressor-like 1 0.76 
    GATA1 GATA binding protein 1 (globin transcription factor 1) 0.77 
Cell adhesion   
    CEECAM1 Cerebral endothelial cell adhesion molecule 1 0.68 
    MADCAM1 Mucosal vascular addressin cell adhesion molecule 1 0.83 
Oncogene   
    RAB17 RAB17, member RAS oncogene family 0.78 
    RAB35 RAB35, member RAS oncogene family 0.85 
    RHOD Ras homolog gene family, member D 0.74 

A complete list of genes is available in Table S4.

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