Phenotype of 5 tonsillar B-cell subpopulations
Marker . | Population . | ||||
---|---|---|---|---|---|
Naive . | Pro-GC . | Pre-GC . | GC . | Memory . | |
CD5 | − | −/+ | − | +/− | −/+ |
CD10 | − | − | + | + | − |
CD19 | + | + | + | + | + |
CD20 | + | + | + | ++ | ++ |
CD21 | +/− | + | −/+ | + | + |
CD23 | −/+ | − | |||
CD27 | − | − | − | − | + |
CD38 | − | − | + | + | − |
CD39 | − | +/− | − | − | −/+ |
CD40 | + | ++ | + | + | + |
CD44 | + | + | + | + | + |
CD69 | −/+ | − | − | − | |
CD71 | − | + | + | + | |
CD77 | − | −/+ | +/− | ++/− | −/+ |
CD80 | + | +++ | ++ | ++ | + |
CD86 | + | ++ | +++ | ++ | + |
CD95 | − | + | + | + | − |
HLA-DR | + | + | + | ++ | + |
IgD | + | + | + | − | − |
IgM | −/+ | −/+ | −/+ | − | − |
Marker . | Population . | ||||
---|---|---|---|---|---|
Naive . | Pro-GC . | Pre-GC . | GC . | Memory . | |
CD5 | − | −/+ | − | +/− | −/+ |
CD10 | − | − | + | + | − |
CD19 | + | + | + | + | + |
CD20 | + | + | + | ++ | ++ |
CD21 | +/− | + | −/+ | + | + |
CD23 | −/+ | − | |||
CD27 | − | − | − | − | + |
CD38 | − | − | + | + | − |
CD39 | − | +/− | − | − | −/+ |
CD40 | + | ++ | + | + | + |
CD44 | + | + | + | + | + |
CD69 | −/+ | − | − | − | |
CD71 | − | + | + | + | |
CD77 | − | −/+ | +/− | ++/− | −/+ |
CD80 | + | +++ | ++ | ++ | + |
CD86 | + | ++ | +++ | ++ | + |
CD95 | − | + | + | + | − |
HLA-DR | + | + | + | ++ | + |
IgD | + | + | + | − | − |
IgM | −/+ | −/+ | −/+ | − | − |
Relative MFIs of different levels are indicated by multiple + signs. The order of + or − signs indicates predominant population.