Table 2

Correlation of clinical parameters with risk groups in the training cohort (n = 351)

CharacteristicLow-risk, %High-risk, %P
Age, 65 y or older 20 20 .856 
Albumin, less than 35 g/L 13 35 .001 
β2-microglobulin 
    Less than 297.5 nM 62 42 .005 
    297.5 nM or more to less than 467.5 nM 20 20  
    467.5 nM or more 19 40  
C-reactive protein, 4 mg/L or more 51 62 .235 
LDH, 190 IU/L or more 30 59 < .001 
Interphase FISH-defined del13 31 49 .031 
Cytogenetic abnormalities 26 70 < .001 
GEP-based translocations 
    CCND1 20 < .001 
    MMSET 12 28  
    MAF/MAFB  
    No spike 65 63  
CharacteristicLow-risk, %High-risk, %P
Age, 65 y or older 20 20 .856 
Albumin, less than 35 g/L 13 35 .001 
β2-microglobulin 
    Less than 297.5 nM 62 42 .005 
    297.5 nM or more to less than 467.5 nM 20 20  
    467.5 nM or more 19 40  
C-reactive protein, 4 mg/L or more 51 62 .235 
LDH, 190 IU/L or more 30 59 < .001 
Interphase FISH-defined del13 31 49 .031 
Cytogenetic abnormalities 26 70 < .001 
GEP-based translocations 
    CCND1 20 < .001 
    MMSET 12 28  
    MAF/MAFB  
    No spike 65 63  
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