Table 2 MOI and parasite density in HbAS... | American Society of Hematology

Table 2

MOI and parasite density in HbAS versus HbAA children

Outcome	HbAA, mean (range)	HbAS, mean (range)	Relative MOI (95% CI)	P
MOI*
Overall	2.64 (1-15)	2.12 (1-11)	0.79 (0.65-0.95)	.01
Symptomatic malaria	2.61 (1-15)	2.17 (1-8)	0.80 (0.68-0.95)	.01
Asymptomatic parasitemia	2.68 (1-15)	2.08 (1-11)	0.78 (0.60-1.02)	.07
Parasite density†	Geometric mean (IQR)	Geometric mean (IQR)	Relative density (95% CI)	P
Overall	4208 (640-38 480)	1719 (232-13 580)	0.42 (0.26-0.68)	< .001
Symptomatic malaria	11 955 (3000-65 520)	5661 (1100-42 040)	0.49 (0.29-0.85)	.01
Asymptomatic parasitemia	708 (192-2280)	544 (96-2140)	0.76 (0.49-1.20)	.24

Outcome	HbAA, mean (range)	HbAS, mean (range)	Relative MOI (95% CI)	P
MOI*
Overall	2.64 (1-15)	2.12 (1-11)	0.79 (0.65-0.95)	.01
Symptomatic malaria	2.61 (1-15)	2.17 (1-8)	0.80 (0.68-0.95)	.01
Asymptomatic parasitemia	2.68 (1-15)	2.08 (1-11)	0.78 (0.60-1.02)	.07
Parasite density†	Geometric mean (IQR)	Geometric mean (IQR)	Relative density (95% CI)	P
Overall	4208 (640-38 480)	1719 (232-13 580)	0.42 (0.26-0.68)	< .001
Symptomatic malaria	11 955 (3000-65 520)	5661 (1100-42 040)	0.49 (0.29-0.85)	.01
Asymptomatic parasitemia	708 (192-2280)	544 (96-2140)	0.76 (0.49-1.20)	.24

IQR indicates interquartile range.

Multiplicity of infection (MOI) was defined as the number of unique parasite genotypes detected in a positive blood smear.

Parasite density was measured via thin smear as parasites per microliter.