Table 4 Long-term hematopoiesis * in... | American Society of Hematology

Table 4

Long-term hematopoiesis* in culture of sorted CD34⁺ACE⁺ and CD34⁺ACE⁻ populations and frequency† of progenitors endowed with this ability

Age, wk	Fetal liver			BM
	CD34⁺ACE⁺		CD34⁺ACE⁻	CD34⁺ACE⁺		CD34⁺ACE⁻
	Hematopoiesis*	Frequency†	Hematopoiesis*	Hematopoiesis*	Frequency†	Hematopoiesis*
7.5	2/3	1/614	0/3	ND	ND	ND
8.5-9.5	3/3	1/394	0/3	ND	ND	ND
10.3	1/1	1/149	0/1	ND	ND	ND
14-15	1/1	1/18	0/1	2/2	1/131	0/2
16	3/3	1/37	0/3	1/1	1/226	0/1
18-19	1/1	1/100	0/1	ND	ND	ND
20-22	2/2	1/130	0/2	2/2	1/184	2/2

Age, wk	Fetal liver			BM
	CD34⁺ACE⁺		CD34⁺ACE⁻	CD34⁺ACE⁺		CD34⁺ACE⁻
	Hematopoiesis*	Frequency†	Hematopoiesis*	Hematopoiesis*	Frequency†	Hematopoiesis*
7.5	2/3	1/614	0/3	ND	ND	ND
8.5-9.5	3/3	1/394	0/3	ND	ND	ND
10.3	1/1	1/149	0/1	ND	ND	ND
14-15	1/1	1/18	0/1	2/2	1/131	0/2
16	3/3	1/37	0/3	1/1	1/226	0/1
18-19	1/1	1/100	0/1	ND	ND	ND
20-22	2/2	1/130	0/2	2/2	1/184	2/2

ND indicates not done.

Ability to give rise to hematopoiesis in culture for at least 35 days.

Frequency of progenitors present in sorted populations able to establish long-term hematopoiesis as estimated by limiting-dilution analysis.