Graft characteristics, hematopoietic recovery, and incidence of GVHD
| Characteristic . | . |
|---|---|
| Total no. patients | 64 |
| Donor age, y, median (range) | 44 (19-78) |
| Donor type, no. (%) | |
| Matched related | 30 (46.9) |
| Matched unrelated | 30 (46.9) |
| Mismatched related | 4 (6.2) |
| Stem-cell source, no. (%) | |
| Bone marrow | 38 (59.4) |
| Peripheral blood | 26 (40.6) |
| Donor/recipient sex match, no. (%) | |
| F-M | 14 (21.9) |
| Other | 50 (78.1) |
| Donor/recipient CMV status, no. (%) | |
| Negative-negative | 8 (12.5) |
| Others | 50 (78.1) |
| Data not available | 6 (9.4) |
| ABO donor/recipient mismatch, no. (%) | 25 (39.1) |
| Graft composition, median (range) | |
| Total nucleated cells for bone marrow, ×108/kg | 2.3 (0.5-3.9) |
| Total nucleated cells for peripheral blood, ×108/kg | 5.8 (2.6-15.5) |
| CD34+ for bone marrow, ×106/kg | 3.4 (0.4-8.6) |
| CD34+ for peripheral blood, ×106/kg | 4.4 (2.3-6.0) |
| Days to ANC higher than 0.5 ×109/L, median (range) | 14 (9-46) |
| Days to platelet higher than 20 ×109/L, median (range) | 18 (9-118) |
| Acute GVHD, no. (%) | |
| Grades II to IV | 20 (31.2) |
| Grades III to IV | 10 (15.6) |
| Chronic GVHD, no. (%) | |
| Limited and extensive | 17 (30.9) |
| Extensive only | 11 (20.0) |
| Characteristic . | . |
|---|---|
| Total no. patients | 64 |
| Donor age, y, median (range) | 44 (19-78) |
| Donor type, no. (%) | |
| Matched related | 30 (46.9) |
| Matched unrelated | 30 (46.9) |
| Mismatched related | 4 (6.2) |
| Stem-cell source, no. (%) | |
| Bone marrow | 38 (59.4) |
| Peripheral blood | 26 (40.6) |
| Donor/recipient sex match, no. (%) | |
| F-M | 14 (21.9) |
| Other | 50 (78.1) |
| Donor/recipient CMV status, no. (%) | |
| Negative-negative | 8 (12.5) |
| Others | 50 (78.1) |
| Data not available | 6 (9.4) |
| ABO donor/recipient mismatch, no. (%) | 25 (39.1) |
| Graft composition, median (range) | |
| Total nucleated cells for bone marrow, ×108/kg | 2.3 (0.5-3.9) |
| Total nucleated cells for peripheral blood, ×108/kg | 5.8 (2.6-15.5) |
| CD34+ for bone marrow, ×106/kg | 3.4 (0.4-8.6) |
| CD34+ for peripheral blood, ×106/kg | 4.4 (2.3-6.0) |
| Days to ANC higher than 0.5 ×109/L, median (range) | 14 (9-46) |
| Days to platelet higher than 20 ×109/L, median (range) | 18 (9-118) |
| Acute GVHD, no. (%) | |
| Grades II to IV | 20 (31.2) |
| Grades III to IV | 10 (15.6) |
| Chronic GVHD, no. (%) | |
| Limited and extensive | 17 (30.9) |
| Extensive only | 11 (20.0) |
F indicates female; M, male; ANC, absolute neutrophil count; and CMV, cytomegalovirus.