Clinical characteristics of 6 participants (with either HbSS or HbSβ° thalassemia) between 5 and 15 years of age who had a clinical diagnosis of hypertension in the SIT Trial or started hypertensive medications
| Age, y . | Sex . | Medication . | BP . | Indication . | MRI results . |
|---|---|---|---|---|---|
| 6 | Female | Enalapril | 123/74 | Enalapril for hypertension and congenital single kidney | 1 faint lesion in the right frontal lobe white matter |
| Started 2 y before the diagnosis of SCI | 1 lesion in the posterior corpus callosum | ||||
| 9 | Male | Enalapril | 110/57 | Enalapril for mitral valve prolapse | 5-mm lesion in the left centrum semiovale |
| Started 8 y before the diagnosis of SCI | |||||
| 14 | Male | Lisinopril | 126/62 | Lisinopril for hypertension | High parietal white matter lesion on the right |
| Started 1.5 y before the diagnosis of SCI | |||||
| 11 | Female | Atenolol | 114/63 | Atenolol for hypertension | Diffuse, bihemispheric ischemic injury |
| Started 2 mo before the diagnosis of SCI | |||||
| 11 | Male | Enalapril | 104/58 | Enalapril for hypertension | 2 lesions in the left frontal lobe |
| Started 6 y before the diagnosis of SCI | Bilateral posterior perventricular white matter abnormality | ||||
| 5 | Male | Enalapril | 135/67 | Enalapril for hypertension | Does not have an infarct-like lesion |
| Started 2 y before the diagnosis of SCI |
| Age, y . | Sex . | Medication . | BP . | Indication . | MRI results . |
|---|---|---|---|---|---|
| 6 | Female | Enalapril | 123/74 | Enalapril for hypertension and congenital single kidney | 1 faint lesion in the right frontal lobe white matter |
| Started 2 y before the diagnosis of SCI | 1 lesion in the posterior corpus callosum | ||||
| 9 | Male | Enalapril | 110/57 | Enalapril for mitral valve prolapse | 5-mm lesion in the left centrum semiovale |
| Started 8 y before the diagnosis of SCI | |||||
| 14 | Male | Lisinopril | 126/62 | Lisinopril for hypertension | High parietal white matter lesion on the right |
| Started 1.5 y before the diagnosis of SCI | |||||
| 11 | Female | Atenolol | 114/63 | Atenolol for hypertension | Diffuse, bihemispheric ischemic injury |
| Started 2 mo before the diagnosis of SCI | |||||
| 11 | Male | Enalapril | 104/58 | Enalapril for hypertension | 2 lesions in the left frontal lobe |
| Started 6 y before the diagnosis of SCI | Bilateral posterior perventricular white matter abnormality | ||||
| 5 | Male | Enalapril | 135/67 | Enalapril for hypertension | Does not have an infarct-like lesion |
| Started 2 y before the diagnosis of SCI |