CXCR5 expression in mutated, CD38 CLL and nonmutated, CD38+ CLL
| CLL sample no. . | IgVH % deviation . | % CD38+ . | Isotype control . | Mean CXCR5 . | CXCR5 MFIR . |
|---|---|---|---|---|---|
| Mutated, CD38− | |||||
| ––––1 | 8.7 | 2 | 2.1 | 249.0 | 120.3 |
| ––––2 | 6.1 | 1 | 2.7 | 190.0 | 71.7 |
| ––––3 | 8.8 | 0.4 | 2.8 | 371.0 | 131.1 |
| ––––4 | 5.1 | 1 | 2.1 | 255.0 | 123.8 |
| ––––5 | 4.8 | 0.7 | 2.4 | 279.0 | 118.2 |
| ––––6 | 7.8 | 0.8 | 2.7 | 198.0 | 73.1 |
| ––––Mean | — | — | 2.4 | 257.0 | 106.4 |
| ––––STDV | — | — | 0.3 | 65.6 | 26.7 |
| Nonmutated, CD38+ | |||||
| ––––7 | 0.7 | 97 | 2.3 | 285.0 | 123.4 |
| ––––8 | 0 | 54 | 2.3 | 129.0 | 56.6 |
| ––––9 | 0 | 21.3 | 2.2 | 401.0 | 186.5 |
| ––––10 | 0.7 | 62 | 3.3 | 297.0 | 91.1 |
| ––––11 | 0 | 94 | 2.5 | 212.0 | 86.2 |
| ––––Mean | — | — | 2.5 | 264.8 | 108.8 |
| ––––STDV | — | — | 0.4 | 101.5 | 49.5 |
| CLL sample no. . | IgVH % deviation . | % CD38+ . | Isotype control . | Mean CXCR5 . | CXCR5 MFIR . |
|---|---|---|---|---|---|
| Mutated, CD38− | |||||
| ––––1 | 8.7 | 2 | 2.1 | 249.0 | 120.3 |
| ––––2 | 6.1 | 1 | 2.7 | 190.0 | 71.7 |
| ––––3 | 8.8 | 0.4 | 2.8 | 371.0 | 131.1 |
| ––––4 | 5.1 | 1 | 2.1 | 255.0 | 123.8 |
| ––––5 | 4.8 | 0.7 | 2.4 | 279.0 | 118.2 |
| ––––6 | 7.8 | 0.8 | 2.7 | 198.0 | 73.1 |
| ––––Mean | — | — | 2.4 | 257.0 | 106.4 |
| ––––STDV | — | — | 0.3 | 65.6 | 26.7 |
| Nonmutated, CD38+ | |||||
| ––––7 | 0.7 | 97 | 2.3 | 285.0 | 123.4 |
| ––––8 | 0 | 54 | 2.3 | 129.0 | 56.6 |
| ––––9 | 0 | 21.3 | 2.2 | 401.0 | 186.5 |
| ––––10 | 0.7 | 62 | 3.3 | 297.0 | 91.1 |
| ––––11 | 0 | 94 | 2.5 | 212.0 | 86.2 |
| ––––Mean | — | — | 2.5 | 264.8 | 108.8 |
| ––––STDV | — | — | 0.4 | 101.5 | 49.5 |
The boldface numbers represent the mean and standard deviation of the fluorescence intensities for the isotype controls, CXCR5, and CXCR5 MFIR.
— indicates not applicable; STDV, standard deviation.