Clinical activity by dose
| Dose (mg/m2 per day) . | Number of patients (N = 51) . | Leukemia cutis resolved (n = 3) . | Leukocytosis/differentiation (n = 9) . | Overall response (n = 2) . |
|---|---|---|---|---|
| 12 | 1 | 0 | 0 | |
| 24 | 5 | 0 | 1 | |
| 36 | 4 | 1 | 2 | |
| 54 | 6 | 1 | 1 | 1 CR |
| 54 (28-d CIV) | 8 | 1 | 1 | 1 CR |
| 80 | 3 | 0 | 2 | |
| 90 (28-d CIV) | 24 | 0 | 2 |
| Dose (mg/m2 per day) . | Number of patients (N = 51) . | Leukemia cutis resolved (n = 3) . | Leukocytosis/differentiation (n = 9) . | Overall response (n = 2) . |
|---|---|---|---|---|
| 12 | 1 | 0 | 0 | |
| 24 | 5 | 0 | 1 | |
| 36 | 4 | 1 | 2 | |
| 54 | 6 | 1 | 1 | 1 CR |
| 54 (28-d CIV) | 8 | 1 | 1 | 1 CR |
| 80 | 3 | 0 | 2 | |
| 90 (28-d CIV) | 24 | 0 | 2 |