Table 2.

HR for death or leukemic transformation in a multivariate model

HR (95% CI)P
Patients with CD34+cell samples (n = 100)   
 Death   
  Hemoglobin (g/dL) 0.54 (0.37-0.77) <.001 
  Bone marrow blast (%) 1.05 (1.02-1.09) .003 
  Age (y) 1.09 (1.02-1.16) .009 
  IMP vs EMK subgroup 4.87 (1.25-19.0) .02 
 Leukemic transformation*   
Patients with only BMMNC samples (n = 114)   
 Death   
  Bone marrow blast (%) 1.11 (1.06-1.16) <.001 
  Hemoglobin (g/dL) 0.67 (0.52-0.86) .001 
  IMP vs EMK subgroup 2.90 (1.10-7.62) .03 
  Absolute neutrophil count (×109/L) 1.12 (1.00-1.26) .05 
  Cytogenetic abnormalities 2.16 (0.92-5.07) .08 
  Platelet (×109/L) 0.996 (0.992-1.001) .12 
 Leukemic transformation   
  Bone marrow blast (%) 1.14 (1.08-1.21) <.001 
  IMP vs EMK subgroup 5.86 (1.59-21.6) .008 
  Hemoglobin (g/dL) 0.80 (0.66-0.98) .03 
HR (95% CI)P
Patients with CD34+cell samples (n = 100)   
 Death   
  Hemoglobin (g/dL) 0.54 (0.37-0.77) <.001 
  Bone marrow blast (%) 1.05 (1.02-1.09) .003 
  Age (y) 1.09 (1.02-1.16) .009 
  IMP vs EMK subgroup 4.87 (1.25-19.0) .02 
 Leukemic transformation*   
Patients with only BMMNC samples (n = 114)   
 Death   
  Bone marrow blast (%) 1.11 (1.06-1.16) <.001 
  Hemoglobin (g/dL) 0.67 (0.52-0.86) .001 
  IMP vs EMK subgroup 2.90 (1.10-7.62) .03 
  Absolute neutrophil count (×109/L) 1.12 (1.00-1.26) .05 
  Cytogenetic abnormalities 2.16 (0.92-5.07) .08 
  Platelet (×109/L) 0.996 (0.992-1.001) .12 
 Leukemic transformation   
  Bone marrow blast (%) 1.14 (1.08-1.21) <.001 
  IMP vs EMK subgroup 5.86 (1.59-21.6) .008 
  Hemoglobin (g/dL) 0.80 (0.66-0.98) .03 
*

Failure in convergence due to no leukemic transformation in the EMK subgroup.

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