Chimerism and GVHD data for HLH patients with reactivations
ID . | Day of HLH reactivation* . | Type of HLH reactivation . | Day of grade II-IV aGVHD onset* . | Day of cGVHD onset* . | Pre/Post HLH reactivation . | Day unfractionated sample collected* . | Type of unfractionated sample . | Unfractionated sample, % donor . | T-cell sample collected* . | Type of T-cell sample . | T-cell sample, % donor . | Minimum recorded chimerism . | ||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
% Donor . | Day of sample . | Sample type . | ||||||||||||
8 | 139 | Systemic | 97 | 143 | Pre Post | 97 143 | Blood Blood | 10 71 | 97 143 | Blood Blood | 84 7 | 2 | 170 | Marrow |
15 | 314 | Systemic | No reported aGVHD | No reported cGVHD | Pre Post | 181 315 | Blood Marrow | 14 7 | 181 315 | Blood Blood | 37 14 | 7 | 318 | Marrow |
20 | 61 | Systemic | No reported aGVHD | 298 | Pre Post | — — | — — | — — | 39 53 | Blood Blood | 56 61 | 56 | 39 | T-cell |
24 | 138 328 | CNS CNS | No reported aGVHD | 155 | Pre Post Post (2nd activation) | 96 186 333 | Blood Blood Blood | 100 98 90 | 96 186 333 | Blood Blood Blood | 100 100 97 | 90 | 27 | T-cell |
28 | 88 | Both | 35 | No reported cGVHD | Pre Post | 56 84 | Blood Blood | 100 100 | — — | — — | — — | 100 | 28 | Marrow |
ID . | Day of HLH reactivation* . | Type of HLH reactivation . | Day of grade II-IV aGVHD onset* . | Day of cGVHD onset* . | Pre/Post HLH reactivation . | Day unfractionated sample collected* . | Type of unfractionated sample . | Unfractionated sample, % donor . | T-cell sample collected* . | Type of T-cell sample . | T-cell sample, % donor . | Minimum recorded chimerism . | ||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
% Donor . | Day of sample . | Sample type . | ||||||||||||
8 | 139 | Systemic | 97 | 143 | Pre Post | 97 143 | Blood Blood | 10 71 | 97 143 | Blood Blood | 84 7 | 2 | 170 | Marrow |
15 | 314 | Systemic | No reported aGVHD | No reported cGVHD | Pre Post | 181 315 | Blood Marrow | 14 7 | 181 315 | Blood Blood | 37 14 | 7 | 318 | Marrow |
20 | 61 | Systemic | No reported aGVHD | 298 | Pre Post | — — | — — | — — | 39 53 | Blood Blood | 56 61 | 56 | 39 | T-cell |
24 | 138 328 | CNS CNS | No reported aGVHD | 155 | Pre Post Post (2nd activation) | 96 186 333 | Blood Blood Blood | 100 98 90 | 96 186 333 | Blood Blood Blood | 100 100 97 | 90 | 27 | T-cell |
28 | 88 | Both | 35 | No reported cGVHD | Pre Post | 56 84 | Blood Blood | 100 100 | — — | — — | — — | 100 | 28 | Marrow |
Last available chimerism data from before HLH reactivation and chimerism reported on the HLH reactivation case report form.
Day from transplant.