Characteristics and outcomes of Medicare beneficiaries with leukemia, stratified by TD status before death or hospice enrollment
| . | All patients (n = 21 033) . | Not transfusion dependent (n = 16 892) . | Transfusion dependent (n = 4141) . |
|---|---|---|---|
| Leukemia histology | |||
| AML | 8 918 (43) | 6 082 (36) | 2836 (68) |
| ALL | 652 (3) | 511 (3) | 141 (3) |
| CLL | 8 420 (40) | 7 821 (46) | 599 (15) |
| CML | 1 536 (7) | 1 305 (8) | 231 (6) |
| CMML | 1 507 (7) | 1 173 (7) | 334 (8) |
| Age group, y | |||
| 65 to <70 | 2 528 (12) | 1 914 (11) | 614 (15) |
| 70 to <75 | 4 193 (20) | 3 203 (19) | 990 (24) |
| 75 to <80 | 5 133 (24) | 4 055 (24) | 1078 (26) |
| 80 to <85 | 4 804 (23) | 3 915 (23) | 889 (21) |
| ≥85 | 4 375 (21) | 3 805 (23) | 570 (14) |
| Sex | |||
| Female | 9 172 (44) | 7 491 (44) | 1681 (41) |
| Male | 11 861 (56) | 9 401 (56) | 2460 (59) |
| Race/ethnicity | |||
| White non-Hispanic | 18 342 (87) | 14 784 (88) | 3558 (86) |
| White Hispanic | 753 (4) | 582 (3) | 171 (4) |
| Black | 1 267 (6) | 1 049 (6) | 218 (5) |
| Asian or other | 671 (3) | 477 (3) | 194 (5) |
| Marital status | |||
| Married | 10 891 (52) | 8 438 (50) | 2453 (59) |
| Other | 10 142 (48) | 8 454 (50) | 1688 (41) |
| Medicaid coinsurance | |||
| No | 18 159 (86) | 14 535 (86) | 3624 (88) |
| Yes | 2 874 (14) | 2 357 (14) | 517 (13) |
| Comorbidity index* | |||
| 0 | 4 211 (20) | 3 339 (20) | 872 (21) |
| 1 | 4 582 (22) | 3 604 (21) | 978 (24) |
| 2 | 4 126 (20) | 3 281 (19) | 845 (20) |
| 3 | 3 046 (15) | 2 487 (15) | 559 (14) |
| 4 | 2 151 (10) | 1 729 (10) | 422 (10) |
| ≥5 | 2 917 (14) | 2 452 (15) | 465 (11) |
| Performance status* | |||
| Not poor | 13 732 (65) | 10 703 (63) | 3029 (73) |
| Poor | 7 301 (35) | 6 189 (37) | 1112 (27) |
| Dementia* | |||
| Absent | 19 073 (91) | 15 054 (89) | 4019 (97) |
| Present | 1 960 (9) | 1 838 (11) | 122 (3) |
| Poverty prevalence (%)† | |||
| 0 to <5 | 5 900 (28) | 4 614 (27) | 1286 (31) |
| 5 to <10 | 5 865 (28) | 4 700 (28) | 1165 (28) |
| 10 to <20 | 5 391 (26) | 4 371 (26) | 1020 (25) |
| ≥20 | 3 158 (15) | 2 611 (16) | 547 (13) |
| Unrecorded | 719 (3) | 596 (4) | 123 (3) |
| Population size† | |||
| ≥1 million | 11 458 (54) | 9 099 (54) | 2359 (57) |
| 250 000-1 million | 5 879 (28) | 4 804 (28) | 1075 (26) |
| <250 000 | 3 696 (18) | 2 989 (18) | 707 (17) |
| Hospice enrollment at death | |||
| No | 11 803 (56) | 9 631 (57) | 2172 (52) |
| Yes | 9 230 (44) | 7 261 (43) | 1969 (48) |
| Chemotherapy within 14 d of death | |||
| No | 18 667 (89) | 15 107 (89) | 3560 (86) |
| Yes | 2 366 (11) | 1 785 (11) | 581 (14) |
| Inpatient death | |||
| No | 11 908 (57) | 9 645 (57) | 2263 (55) |
| Yes | 9 125 (43) | 7 247 (43) | 1878 (45) |
| ICU within 30 d of death | |||
| No | 13 636 (65) | 11 054 (65) | 2582 (62) |
| Yes | 7 397 (35) | 5 838 (35) | 1559 (38) |
| Less than 3 d on hospice (n = 9230)‡ | |||
| No | 7 360 (80) | 5 915 (82) | 1445 (73) |
| Yes | 1 870 (20) | 1 346 (19) | 524 (27) |
| Outpatient hospice referral (n = 9230)‡ | |||
| No | 4 468 (48) | 3 380 (47) | 1088 (55) |
| Yes | 4 762 (52) | 3 881 (53) | 881 (45) |
| . | All patients (n = 21 033) . | Not transfusion dependent (n = 16 892) . | Transfusion dependent (n = 4141) . |
|---|---|---|---|
| Leukemia histology | |||
| AML | 8 918 (43) | 6 082 (36) | 2836 (68) |
| ALL | 652 (3) | 511 (3) | 141 (3) |
| CLL | 8 420 (40) | 7 821 (46) | 599 (15) |
| CML | 1 536 (7) | 1 305 (8) | 231 (6) |
| CMML | 1 507 (7) | 1 173 (7) | 334 (8) |
| Age group, y | |||
| 65 to <70 | 2 528 (12) | 1 914 (11) | 614 (15) |
| 70 to <75 | 4 193 (20) | 3 203 (19) | 990 (24) |
| 75 to <80 | 5 133 (24) | 4 055 (24) | 1078 (26) |
| 80 to <85 | 4 804 (23) | 3 915 (23) | 889 (21) |
| ≥85 | 4 375 (21) | 3 805 (23) | 570 (14) |
| Sex | |||
| Female | 9 172 (44) | 7 491 (44) | 1681 (41) |
| Male | 11 861 (56) | 9 401 (56) | 2460 (59) |
| Race/ethnicity | |||
| White non-Hispanic | 18 342 (87) | 14 784 (88) | 3558 (86) |
| White Hispanic | 753 (4) | 582 (3) | 171 (4) |
| Black | 1 267 (6) | 1 049 (6) | 218 (5) |
| Asian or other | 671 (3) | 477 (3) | 194 (5) |
| Marital status | |||
| Married | 10 891 (52) | 8 438 (50) | 2453 (59) |
| Other | 10 142 (48) | 8 454 (50) | 1688 (41) |
| Medicaid coinsurance | |||
| No | 18 159 (86) | 14 535 (86) | 3624 (88) |
| Yes | 2 874 (14) | 2 357 (14) | 517 (13) |
| Comorbidity index* | |||
| 0 | 4 211 (20) | 3 339 (20) | 872 (21) |
| 1 | 4 582 (22) | 3 604 (21) | 978 (24) |
| 2 | 4 126 (20) | 3 281 (19) | 845 (20) |
| 3 | 3 046 (15) | 2 487 (15) | 559 (14) |
| 4 | 2 151 (10) | 1 729 (10) | 422 (10) |
| ≥5 | 2 917 (14) | 2 452 (15) | 465 (11) |
| Performance status* | |||
| Not poor | 13 732 (65) | 10 703 (63) | 3029 (73) |
| Poor | 7 301 (35) | 6 189 (37) | 1112 (27) |
| Dementia* | |||
| Absent | 19 073 (91) | 15 054 (89) | 4019 (97) |
| Present | 1 960 (9) | 1 838 (11) | 122 (3) |
| Poverty prevalence (%)† | |||
| 0 to <5 | 5 900 (28) | 4 614 (27) | 1286 (31) |
| 5 to <10 | 5 865 (28) | 4 700 (28) | 1165 (28) |
| 10 to <20 | 5 391 (26) | 4 371 (26) | 1020 (25) |
| ≥20 | 3 158 (15) | 2 611 (16) | 547 (13) |
| Unrecorded | 719 (3) | 596 (4) | 123 (3) |
| Population size† | |||
| ≥1 million | 11 458 (54) | 9 099 (54) | 2359 (57) |
| 250 000-1 million | 5 879 (28) | 4 804 (28) | 1075 (26) |
| <250 000 | 3 696 (18) | 2 989 (18) | 707 (17) |
| Hospice enrollment at death | |||
| No | 11 803 (56) | 9 631 (57) | 2172 (52) |
| Yes | 9 230 (44) | 7 261 (43) | 1969 (48) |
| Chemotherapy within 14 d of death | |||
| No | 18 667 (89) | 15 107 (89) | 3560 (86) |
| Yes | 2 366 (11) | 1 785 (11) | 581 (14) |
| Inpatient death | |||
| No | 11 908 (57) | 9 645 (57) | 2263 (55) |
| Yes | 9 125 (43) | 7 247 (43) | 1878 (45) |
| ICU within 30 d of death | |||
| No | 13 636 (65) | 11 054 (65) | 2582 (62) |
| Yes | 7 397 (35) | 5 838 (35) | 1559 (38) |
| Less than 3 d on hospice (n = 9230)‡ | |||
| No | 7 360 (80) | 5 915 (82) | 1445 (73) |
| Yes | 1 870 (20) | 1 346 (19) | 524 (27) |
| Outpatient hospice referral (n = 9230)‡ | |||
| No | 4 468 (48) | 3 380 (47) | 1088 (55) |
| Yes | 4 762 (52) | 3 881 (53) | 881 (45) |