Table 1

Baseline patient characteristics and laboratory test data among Olmsted County, MN residents with incident DVT or PE in 1984-1997

Baseline characteristic and laboratory test dataResults (N = 1166)
Patient age at incident DVT or PE, y, mean ± SD (range) 63.2 ± 19.4 (0-100) 
Female, n (%) 637 (55) 
BMI, kg/m2, mean ± SD (range) 27.6 ± 6.7 (6.2-72.3) 
Major VTE risk factors, n (%)* 
    Hospitalization for surgery 350 (30) 
    Hospitalization for acute medical illness 251 (22) 
    Nursing home confinement 110 (9) 
    Trauma/fracture 163 (14) 
    Active cancer 263 (23) 
    Neurologic disease with leg paresis 75 (6) 
    Pregnancy or postpartum (n = 635) 35 (6) 
    Oral contraceptive or hormone therapy among women 136 (12) 
    Idiopathic 302 (26) 
    Congestive heart failure 209 (18) 
    Chronic lung disease 206 (18) 
    Chronic liver disease 11 (1) 
    Chronic renal disease 31 (3) 
Baseline laboratory test data, mean ± SD (range)  
    Hemoglobin, g/L 12.1 ± 1.9 (5.5-17.0) 
    Platelet count, ×109/L 264.3 ± 111.3 (36.0-626.0) 
    APTT, s 29.3 ± 10.9 (19.1-97.0) 
    PT, s/INR 12.2 ± 2.0/1.3 ± 0.4 (9.0-22.8/0.9-3.9) 
    Serum creatinine, μmol/L 102.8 ± 48.1 (26.5, 424.3) 
Baseline characteristic and laboratory test dataResults (N = 1166)
Patient age at incident DVT or PE, y, mean ± SD (range) 63.2 ± 19.4 (0-100) 
Female, n (%) 637 (55) 
BMI, kg/m2, mean ± SD (range) 27.6 ± 6.7 (6.2-72.3) 
Major VTE risk factors, n (%)* 
    Hospitalization for surgery 350 (30) 
    Hospitalization for acute medical illness 251 (22) 
    Nursing home confinement 110 (9) 
    Trauma/fracture 163 (14) 
    Active cancer 263 (23) 
    Neurologic disease with leg paresis 75 (6) 
    Pregnancy or postpartum (n = 635) 35 (6) 
    Oral contraceptive or hormone therapy among women 136 (12) 
    Idiopathic 302 (26) 
    Congestive heart failure 209 (18) 
    Chronic lung disease 206 (18) 
    Chronic liver disease 11 (1) 
    Chronic renal disease 31 (3) 
Baseline laboratory test data, mean ± SD (range)  
    Hemoglobin, g/L 12.1 ± 1.9 (5.5-17.0) 
    Platelet count, ×109/L 264.3 ± 111.3 (36.0-626.0) 
    APTT, s 29.3 ± 10.9 (19.1-97.0) 
    PT, s/INR 12.2 ± 2.0/1.3 ± 0.4 (9.0-22.8/0.9-3.9) 
    Serum creatinine, μmol/L 102.8 ± 48.1 (26.5, 424.3) 
*

Hospitalization for surgery or for acute medical illness, nursing home confinement, trauma/fracture, pregnancy/postpartum, and oral contraceptive/hormone therapy had to be documented as present in the 3 months prior to the incident VTE date. Active cancer had to be documented in the 3 months before or after the incident VTE event.

Neurologic disease with leg paresis, congestive heart failure, and chronic lung, liver or renal disease had to be documented as present at any time prior to the incident VTE date.

Baseline laboratory data were based on a subset of the cohort with at least one measurement available (first value used) within the time window between onset of VTE symptoms and start of therapy (median [inter quartile range] time window = 2 [0-6] days); this included n = 280 patients having at least 1 among the 6 laboratory parameters measured, and ranged from n = 151 who had INR data to n = 260 who had hemoglobin data in this time window.

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