Table 5

Molecular response among patients achieving complete cytogenetic response

ResponseImatinib resistant
Imatinib intolerant
Total
No.%No.%No.%
Cumulative response*       
    Patients in subgroup analysis 55  23  78  
    Major 35 64 15 65 50 64 
        Complete 27 49 14 61 41 53 
Reason for exclusion from analysis       
    No assessment† 70  21  91  
    Did not achieve complete cytogenetic response 75  44  119  
ResponseImatinib resistant
Imatinib intolerant
Total
No.%No.%No.%
Cumulative response*       
    Patients in subgroup analysis 55  23  78  
    Major 35 64 15 65 50 64 
        Complete 27 49 14 61 41 53 
Reason for exclusion from analysis       
    No assessment† 70  21  91  
    Did not achieve complete cytogenetic response 75  44  119  
*

Major molecular response = ≥ 3 log reduction from standardized baseline Bcr-Abl:Abl ratio. Complete molecular response = undetectable Bcr-Abl, with a sensitivity of ≥ 5 log. Molecular response was not assessed according to the International Scale.

†

Because of logistical constraints, 4 countries (China, India, Russia, and South Africa) did not evaluate molecular response.

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