Table 1

Percentage of decrease in plasminogen binding, plasmin generation, and chemotaxis resulting from S100A10 depletion

Cell linePlasminogen binding, %Plasmin generation, %Chemotaxis, %Reference
HT1080* (fibrosarcoma) 28 80-95 60 71  
CCL-222* (carcinoma) 45 65 38 83  
LLC* (carcinoma) ND 50 50 Unpublished 
NB4* (APL) 70 70 60 72  
PR9* (histiomonocytic) 72 49 55 72  
Macrophage† 30 45 50 73  
TIME* (endothelial) 50 62 74 53  
MMEC† (endothelial) 40 40 55 53  
Cell linePlasminogen binding, %Plasmin generation, %Chemotaxis, %Reference
HT1080* (fibrosarcoma) 28 80-95 60 71  
CCL-222* (carcinoma) 45 65 38 83  
LLC* (carcinoma) ND 50 50 Unpublished 
NB4* (APL) 70 70 60 72  
PR9* (histiomonocytic) 72 49 55 72  
Macrophage† 30 45 50 73  
TIME* (endothelial) 50 62 74 53  
MMEC† (endothelial) 40 40 55 53  

ND indicates not determined.

*

S100A10 depletion accomplished by shRNA.

†

S100A10 depletion was accomplished by gene knockout.

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