Binding of recombinant proteins to human or murine soluble TF derived from at least 2 independent experiments
| Cofactor . | Protein . | ||||
|---|---|---|---|---|---|
| mFVII . | mFVIIa . | mFVIIa-DVQ . | mFVIIa-VEAY . | rhFVIIa . | |
| hsTF | ND | 86.7 ± 22.8 | 42.4 ± 20.7 | 71.7 ± 22.2 | 12.1 ± 6.0 |
| msTF | ND | 2.0 ± 0.5 | 2.9 ± 0.8 | 3.2 ± 1.9 | ND |
| Cofactor . | Protein . | ||||
|---|---|---|---|---|---|
| mFVII . | mFVIIa . | mFVIIa-DVQ . | mFVIIa-VEAY . | rhFVIIa . | |
| hsTF | ND | 86.7 ± 22.8 | 42.4 ± 20.7 | 71.7 ± 22.2 | 12.1 ± 6.0 |
| msTF | ND | 2.0 ± 0.5 | 2.9 ± 0.8 | 3.2 ± 1.9 | ND |
Values, stated as Kd (nM) were derived from amidolytic activity assays.
ND indicates not determined (data fitting was not possible).