Details and outcomes of 6 patients withdrawn from immunochemotherapy due to severe hepatic toxicity
| Case . | Age, y . | Sex . | Stage . | Hepatic disease at baseline . | AST/ALT at baseline, IU/L . | AST/ALT peak level, IU/L . | No. of cycles of treatment before withdrawal . | Outcome . |
|---|---|---|---|---|---|---|---|---|
| 1 | 76 | F | III | LC | 101/73 | 236/114 | 4 | Died of lymphoma progression |
| 2 | 78 | F | III | CH | 38/25 | 1033/340 | 1 | Died of lymphoma progression |
| 3 | 71 | F | I | LC | 90/82 | 289/128 | 1 | Alive |
| 4 | 59 | M | IV | CH | 31/17 | 211/284 | 4 | Alive |
| 5 | 74 | F | IV | Normal | 50/29 | 274/302 | 3 | Alive |
| 6 | 76 | M | II | Normal | 19/25 | 522/550 | 3 | Alive |
| Case . | Age, y . | Sex . | Stage . | Hepatic disease at baseline . | AST/ALT at baseline, IU/L . | AST/ALT peak level, IU/L . | No. of cycles of treatment before withdrawal . | Outcome . |
|---|---|---|---|---|---|---|---|---|
| 1 | 76 | F | III | LC | 101/73 | 236/114 | 4 | Died of lymphoma progression |
| 2 | 78 | F | III | CH | 38/25 | 1033/340 | 1 | Died of lymphoma progression |
| 3 | 71 | F | I | LC | 90/82 | 289/128 | 1 | Alive |
| 4 | 59 | M | IV | CH | 31/17 | 211/284 | 4 | Alive |
| 5 | 74 | F | IV | Normal | 50/29 | 274/302 | 3 | Alive |
| 6 | 76 | M | II | Normal | 19/25 | 522/550 | 3 | Alive |