Analysis of survival of CAT-13–treated mice after tumor challenge, with or without IL-2 therapy
| Independent experiment no. . | CAT-13–treated surviving mice challenged at day 70 . | CAT-13–treated surviving mice challenged at day 70 + IL-2 . | ||
|---|---|---|---|---|
| Survivors*/total . | Overall survival, percentage . | Survivors†/total . | Overall survival, percentage . | |
| 1 | 1/5 | 20.0‡ | 4/5 | 80.0‡ |
| 2 | 3/7 | 42.8‡ | 5/7 | 71.4‡ |
| 3 | 2/5 | 40.0‡ | 4/5 | 80.0‡ |
| Survivors/total | 6/17 | — | 13/17 | — |
| Mean ± SD, percentage | — | 34.2 ± 12.4 | — | 77.1 ± 4.9 |
| Independent experiment no. . | CAT-13–treated surviving mice challenged at day 70 . | CAT-13–treated surviving mice challenged at day 70 + IL-2 . | ||
|---|---|---|---|---|
| Survivors*/total . | Overall survival, percentage . | Survivors†/total . | Overall survival, percentage . | |
| 1 | 1/5 | 20.0‡ | 4/5 | 80.0‡ |
| 2 | 3/7 | 42.8‡ | 5/7 | 71.4‡ |
| 3 | 2/5 | 40.0‡ | 4/5 | 80.0‡ |
| Survivors/total | 6/17 | — | 13/17 | — |
| Mean ± SD, percentage | — | 34.2 ± 12.4 | — | 77.1 ± 4.9 |
Data are from 3 independent experiments with or without IL-2 treatment after tumor challenge.
— indicates not applicable.
Number of surviving CAT-13–treated mice 70 days after a tumor challenge on day 70.
Number of surviving CAT-13–treated mice that received IL-2 therapy on days 71 and 74 and survived 70 days after a tumor challenge on day 70.
Kruskal-Wallis statistical test, P = .004.