Graft description
Patient no. . | CD34/kg dose at start . | CD34/kg dose after transduction . | CD34, percentage . | GP91, percentage . | Vector copy number . | Vector lot number . | Busulfan AUC, μM/min . |
---|---|---|---|---|---|---|---|
1 | 14 | 43 | 85 | 73 | 4.05 | 1 | 11 324 |
2 | 13.7 | 71 | > 90 | 41 | .8 | 2 | 7638 |
3 | 4.1 | 18.9 | 70 | 25 | .005 | 3 | 7560 |
Patient no. . | CD34/kg dose at start . | CD34/kg dose after transduction . | CD34, percentage . | GP91, percentage . | Vector copy number . | Vector lot number . | Busulfan AUC, μM/min . |
---|---|---|---|---|---|---|---|
1 | 14 | 43 | 85 | 73 | 4.05 | 1 | 11 324 |
2 | 13.7 | 71 | > 90 | 41 | .8 | 2 | 7638 |
3 | 4.1 | 18.9 | 70 | 25 | .005 | 3 | 7560 |
The CD34 doses as well as the marking of the graft as measured by either flow or GP91 expression or PCR for copy number, along with the busulfan levels for each patient are given.