Table 2

Graft description

Patient no.CD34/kg dose at startCD34/kg dose after transductionCD34, percentageGP91, percentageVector copy numberVector lot numberBusulfan AUC, μM/min
14 43 85 73 4.05 11 324 
13.7 71 > 90 41 .8 7638 
4.1 18.9 70 25 .005 7560 
Patient no.CD34/kg dose at startCD34/kg dose after transductionCD34, percentageGP91, percentageVector copy numberVector lot numberBusulfan AUC, μM/min
14 43 85 73 4.05 11 324 
13.7 71 > 90 41 .8 7638 
4.1 18.9 70 25 .005 7560 

The CD34 doses as well as the marking of the graft as measured by either flow or GP91 expression or PCR for copy number, along with the busulfan levels for each patient are given.

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