Anti-CD3 treatment increases systemic TGF-β1
| Mouse no. . | Systemic TGF-β1 (plasma, ng/mL) . |
|---|---|
| Naive mice | |
| 1 | 15.2 ± 0.99 |
| 2 | 10.7 ± 1.3 |
| 3 | 8.6 ± 1.4 |
| FVIII plasmid + anti-CD3 mice | |
| 4, day 3 | 43.25 ± 2.28 |
| 4, day 10 | 39.97 ± 0.27 |
| 5, day 3 | 19.35 ± 0.32 |
| 5, day 10 | 30.97 ± 1.45 |
| 6, day 3 | 7.56 ± 0.35 |
| 6, day 10 | 15.44 ± 0.66 |
| Mouse no. . | Systemic TGF-β1 (plasma, ng/mL) . |
|---|---|
| Naive mice | |
| 1 | 15.2 ± 0.99 |
| 2 | 10.7 ± 1.3 |
| 3 | 8.6 ± 1.4 |
| FVIII plasmid + anti-CD3 mice | |
| 4, day 3 | 43.25 ± 2.28 |
| 4, day 10 | 39.97 ± 0.27 |
| 5, day 3 | 19.35 ± 0.32 |
| 5, day 10 | 30.97 ± 1.45 |
| 6, day 3 | 7.56 ± 0.35 |
| 6, day 10 | 15.44 ± 0.66 |
Systemic TGF-β1 in the plasma was quantified by ELISA with duplicates. Day 3 and day 10 indicate days after the last anti-CD3 injection. Data are mean ± SD of individual mice.