Table 1. Clinical characteristics and... | American Society of Hematology

Table 1.

Clinical characteristics and p-AKT Ser473 expression status of patients with DLBCL

		High p-AKT			Low p-AKT
	Total	n	%	n	%	P
No. of patients	64	35	55	29	45
Age, y						.279
60 or younger	35	17	49	18	51
Older than 60	29	18	62	11	38
Sex						.330
Female	17	11	65	6	35
Male	47	24	51	23	49
Performance status						.133
Lower than 2	40	19	48	21	52
2 or higher	24	16	67	8	33
Stage						.225
I or II	30	14	47	16	53
III or IV	34	21	62	13	38
Extranodal sites involved						.01
1 site	40	17	43	23	57
More than 1 site	24	18	75	6	25
LDH level*						.343
Normal	26	12	46	14	54
High	36	21	58	15	42
IPI						.111
Low to low-intermediate	35	16	46	19	54
High-intermediate to high	29	19	66	10	34
B symptoms						.003
Absent	29	10	35	19	65
Present	35	25	71	10	29
Ki-67 expression (n = 95)						.009
Positive	83	46	55	37	45
Negative	12	2	17	10	83

		High p-AKT			Low p-AKT
	Total	n	%	n	%	P
No. of patients	64	35	55	29	45
Age, y						.279
60 or younger	35	17	49	18	51
Older than 60	29	18	62	11	38
Sex						.330
Female	17	11	65	6	35
Male	47	24	51	23	49
Performance status						.133
Lower than 2	40	19	48	21	52
2 or higher	24	16	67	8	33
Stage						.225
I or II	30	14	47	16	53
III or IV	34	21	62	13	38
Extranodal sites involved						.01
1 site	40	17	43	23	57
More than 1 site	24	18	75	6	25
LDH level*						.343
Normal	26	12	46	14	54
High	36	21	58	15	42
IPI						.111
Low to low-intermediate	35	16	46	19	54
High-intermediate to high	29	19	66	10	34
B symptoms						.003
Absent	29	10	35	19	65
Present	35	25	71	10	29
Ki-67 expression (n = 95)						.009
Positive	83	46	55	37	45
Negative	12	2	17	10	83

LDH categorization is based on the range for normal values in the clinical laboratory at our institution. LDH levels were missing in 2 patients but both patients had a total IPI score of 4 and were categorized in the high-risk group.

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