Relative 5′ c-jun Promoter Activity in BCR-ABL.A54 Versus H7 Parental Cells (+IL-3)
| . | Fold Increase in Luciferase Activity Mean ± SEM* . | |
|---|---|---|
| WT 5′ jun . | MT AP-1 5′jun . | |
| BCR-ABL.A54 | 30.1 ± 8.5 | 1.6 ± 0.4 |
| H7 | 6.4 ± 1.4 | 1.0 ± 0.0 |
| . | Fold Increase in Luciferase Activity Mean ± SEM* . | |
|---|---|---|
| WT 5′ jun . | MT AP-1 5′jun . | |
| BCR-ABL.A54 | 30.1 ± 8.5 | 1.6 ± 0.4 |
| H7 | 6.4 ± 1.4 | 1.0 ± 0.0 |
*Results of three consecutive experiments. Average luminometer units of the A54 cell lysates after WT 5′ jun luciferase transfection was 10,000. Background activity of lysates from mock transfected cells was 100 luminometer units. Data are corrected for luciferase units per β-galactosidase activity × 100. β-Galactosidase activity was exactly comparable between the cell lines.