Table 1. Effect of Salicylates on T-Cell... | American Society of Hematology

Table 1.

Effect of Salicylates on T-Cell Adhesion to TNF-α-Activated HUVEC and Migration Into Collagen

	ASA			NaS
	30 μg/mL	300 μg/mL	600 μg/mL	30 μg/mL	300 μg/mL	600 μg/mL

% of Variation as Compared With Medium
Adherent T cells	−11.8 ± 5^-150	−40.9 ± 9^-151	−41.7 ± 10^-151	−10.4 ± 6^-150	−26.1 ± 6^-151	−30.2 ± 7^-151
Migrated T cells	−39.6 ± 9^-151	−84.4 ± 15^-151	−88.9 ± 12^-151	−41.3 ± 9^-151	−97.3 ± 2^-151	−97.1 ± 2^-151

	ASA			NaS
	30 μg/mL	300 μg/mL	600 μg/mL	30 μg/mL	300 μg/mL	600 μg/mL

% of Variation as Compared With Medium
Adherent T cells	−11.8 ± 5^-150	−40.9 ± 9^-151	−41.7 ± 10^-151	−10.4 ± 6^-150	−26.1 ± 6^-151	−30.2 ± 7^-151
Migrated T cells	−39.6 ± 9^-151	−84.4 ± 15^-151	−88.9 ± 12^-151	−41.3 ± 9^-151	−97.3 ± 2^-151	−97.1 ± 2^-151

Data (mean ± SEM of 12 separate experiments) show the percent decline of the number of adherent and migrated T cells after treatment of T cells with different salicylate concentrations. The mean percentages of adherent and migrated T cells in medium without drugs were 27.4 ± 7 and 5.1 ± 2, respectively.

F0-150

P < .05.

F0-151

P < .001.

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