Table 1.

Plasma ET-1 and PGE2 Levels in Healthy Controls, in Painful Crises, and During Recovery Phase

ET-1 (pg/mL) PGE2 (pg/mL)
Healthy controls (n = 11)  0.535 ± 0.508  316.3 ± 46.9 
Crisis sickle cell (n = 13)  130.9 ± 23.1*-151 825.9 ± 33.9*-151 
Postcrisis sickle cell (n = 13)-152 23.9 ± 9.52* 670.9 ± 61.0* 
ET-1 (pg/mL) PGE2 (pg/mL)
Healthy controls (n = 11)  0.535 ± 0.508  316.3 ± 46.9 
Crisis sickle cell (n = 13)  130.9 ± 23.1*-151 825.9 ± 33.9*-151 
Postcrisis sickle cell (n = 13)-152 23.9 ± 9.52* 670.9 ± 61.0* 

*Statistically significant difference from controls (P < .05).

F0-151

Statistically significant difference from postcrisis levels (P < .05).

F0-152

One to 3 weeks after discharge from hospital.

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