Table 1.

Clinical Data From Patients With HH at the Time of the Experiment and Phagocytic Capacity of Monocytes as Compared With Healthy Donors

Patient No. Sex/Age PI-150Pld/Plp-151Fe Removed (g) Hb (mmol/L) 8.6-10.7-152Serum Ferritin (μg/L) 15-150-152Serum Iron (μmol/L) 14-32-152Fe Saturation 0.25-0.60-152ALAT IU 10-50-152g-GT IU 15-70-152Liver HFE-153
M/31  .57  2.63  16  9.1  2,970  46  0.73 62  31  SF  −/−  
1  M/31  .61  2.84  10.1  2,160  54  0.81  49  30  
2  M/30 .6  1.95  4.4  9.8  271  39  0.74  43  47 N  +/+  
3  M/66  .61  3.2  5.5  7.8  30 7  0.1  52  230  C  +/+  
4  M/65  1.13 1.95  7  9.1  1,179  31  0.76  41  21  +/+  
5  M/66  .73  3   9.5  31  21  0.43 26  24   −/+  
6  M/52  1.17  1.48  8.9  409  36  0.79  9  16  LF  +/+ 
Patient No. Sex/Age PI-150Pld/Plp-151Fe Removed (g) Hb (mmol/L) 8.6-10.7-152Serum Ferritin (μg/L) 15-150-152Serum Iron (μmol/L) 14-32-152Fe Saturation 0.25-0.60-152ALAT IU 10-50-152g-GT IU 15-70-152Liver HFE-153
M/31  .57  2.63  16  9.1  2,970  46  0.73 62  31  SF  −/−  
1  M/31  .61  2.84  10.1  2,160  54  0.81  49  30  
2  M/30 .6  1.95  4.4  9.8  271  39  0.74  43  47 N  +/+  
3  M/66  .61  3.2  5.5  7.8  30 7  0.1  52  230  C  +/+  
4  M/65  1.13 1.95  7  9.1  1,179  31  0.76  41  21  +/+  
5  M/66  .73  3   9.5  31  21  0.43 26  24   −/+  
6  M/52  1.17  1.48  8.9  409  36  0.79  9  16  LF  +/+ 

Abbreviations: Liver damage: N, no damage; LF, light fibrosis; SF, severe fibrosis; C, cirrhosis.

F0-150

Phagocytic index (PI) = total number of erythrocytes/total number of cells.

F0-151

Ratio PI donor (Pld) versus PI patient (Plp).

F0-152

Normal values.

F0-153

C282Y mutation in the HFE gene.

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