Table 1.

Treatment administered to patients with acute promyelocytic leukemia

TreatmentNumber of courses
Newly diagnosedRelapsed
Induction therapy 63 28 
 All-trans RA 61 23  
 9-cisRA 1  
 All-trans RA + chemotherapy 
 Chemotherapy 3  
 BMT 1  
Postremission therapy 54 25  
 Chemotherapy 54 0  
  1 cycle  
  2 cycles  
  3 cycles 42  
  3 cycles + HuM195  
  5 cycles  
  6 cycles  
 All-trans RA maintenance 11  
131I-M195 
 BMT 4  
 AuBMT 2  
 HuM195 maintenance 
TreatmentNumber of courses
Newly diagnosedRelapsed
Induction therapy 63 28 
 All-trans RA 61 23  
 9-cisRA 1  
 All-trans RA + chemotherapy 
 Chemotherapy 3  
 BMT 1  
Postremission therapy 54 25  
 Chemotherapy 54 0  
  1 cycle  
  2 cycles  
  3 cycles 42  
  3 cycles + HuM195  
  5 cycles  
  6 cycles  
 All-trans RA maintenance 11  
131I-M195 
 BMT 4  
 AuBMT 2  
 HuM195 maintenance 

BMT indicates bone marrow transplantation; AuBMT, autologous bone marrow transplantation; 131I-M195, iodine-131–labeled M195 (anti-CD33 monoclonal antibody); HuM195, recombinant humanized M195.