Table 2.

Patients in Whom the PET Scan and Routine BM Biopsy Result Differed

Diagnosis Comment
PET+, biopsy−  
 Focal FDG uptake  
  1. HD (ns)  Normal FDG uptake at biopsy site  
  2. HD (mc)  Normal FDG uptake at biopsy site 
  3. Diffuse large B-cell lymphoma  Normal FDG uptake at biopsy site  
  4. Diffuse large B-cell lymphoma  Normal FDG uptake at biopsy site  
 Diffuse FDG uptake  
  5. HD (ns)  
  6. HD (mc)  
  7. Peripheral T-cell (high grade) lymphoma  
  8. Anaplastic large cell (Ki-1+) lymphoma  
PET−, biopsy+ 
  1. Centroblastic centrocytic lymphoma  No FDG uptake by lymph nodes  
  2. Mantle cell lymphoma  No FDG uptake by lymph nodes  
  3. Mantle cell lymphoma (leukemic variant)  
Diagnosis Comment
PET+, biopsy−  
 Focal FDG uptake  
  1. HD (ns)  Normal FDG uptake at biopsy site  
  2. HD (mc)  Normal FDG uptake at biopsy site 
  3. Diffuse large B-cell lymphoma  Normal FDG uptake at biopsy site  
  4. Diffuse large B-cell lymphoma  Normal FDG uptake at biopsy site  
 Diffuse FDG uptake  
  5. HD (ns)  
  6. HD (mc)  
  7. Peripheral T-cell (high grade) lymphoma  
  8. Anaplastic large cell (Ki-1+) lymphoma  
PET−, biopsy+ 
  1. Centroblastic centrocytic lymphoma  No FDG uptake by lymph nodes  
  2. Mantle cell lymphoma  No FDG uptake by lymph nodes  
  3. Mantle cell lymphoma (leukemic variant)  

Abbreviations: PET−/+, normal/increased FDG uptake within the BM; biopsy−/+, absent/present lymphoma infiltration on marrow biopsy; ns, nodular sclerosis; mc,mixed cellularity HD.

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