Table 6. Effect of T-Cell Dose on the... | American Society of Hematology

Table 6.

Effect of T-Cell Dose on the Quality and Timing of Short-Term Hematological Engraftment after CPC Allogeneic Transplantation

Patients	Disease	Age	Conditioning Regimen	Composition			Days from BMT Graft Infusion Until:
Patients	Disease	Age	Conditioning Regimen	TNC ×10⁶/kg	CD34⁺ ×10⁶/kg	CD3⁺ ×10⁶/kg	ANC > 500/mcl	ANC > 1500/mcl	Plt > 20000/mcl	Plt > 50000/mcl
1	T-ALL	24	TBI/Melphalan	120	7.5	2	12	13	14	50
2	AML	59	TBI/Melphalan	90	9	10	10	11	12	14
3	B-precursor ALL	43	TBI/Melphalan	120	10.5	15	20	21	26	40
4	B-precursor/ALL	18	TBI/Melphalan	290	19.5	15	9	11	10	16
5	B-precursor ALL	45	TBI/Melphalan	80	5.2	40	11	12	11	14
6	T-ALL	31	TBI/Melphalan	470	11.4	50	14	15	14	16
Media		36.7 (18 to 59)		195 (80 to 470)	10.5 (5.2 to 19.5)	22 (2 to 50)	12.6 (9 to 20)	13.8 (11 to 21)	14.5 (10 to 26)	25 (14 to 50)

Patients	Disease	Age	Conditioning Regimen	Composition			Days from BMT Graft Infusion Until:
Patients	Disease	Age	Conditioning Regimen	TNC ×10⁶/kg	CD34⁺ ×10⁶/kg	CD3⁺ ×10⁶/kg	ANC > 500/mcl	ANC > 1500/mcl	Plt > 20000/mcl	Plt > 50000/mcl
1	T-ALL	24	TBI/Melphalan	120	7.5	2	12	13	14	50
2	AML	59	TBI/Melphalan	90	9	10	10	11	12	14
3	B-precursor ALL	43	TBI/Melphalan	120	10.5	15	20	21	26	40
4	B-precursor/ALL	18	TBI/Melphalan	290	19.5	15	9	11	10	16
5	B-precursor ALL	45	TBI/Melphalan	80	5.2	40	11	12	11	14
6	T-ALL	31	TBI/Melphalan	470	11.4	50	14	15	14	16
Media		36.7 (18 to 59)		195 (80 to 470)	10.5 (5.2 to 19.5)	22 (2 to 50)	12.6 (9 to 20)	13.8 (11 to 21)	14.5 (10 to 26)	25 (14 to 50)