Biochemical Characterization of Test Substances
| Substance . | vWF:Ag (U/mL) . | RCoF (U/mL) . | FVIII 2-Stage (U/mL) . | Protein (mg/mL) . |
|---|---|---|---|---|
| rvWF | 104 | 8.0 | <0.001 | 0.86 |
| LMW-rvWF | 213 | 2.9 | <0.001 | 2.80 |
| pdvWF no. 2346641 | 73 | 45.0 | 25 | 6.80 |
| pdvWF no. 2956641 | 147 | 66.0 | 38 | 8.80 |
| Substance . | vWF:Ag (U/mL) . | RCoF (U/mL) . | FVIII 2-Stage (U/mL) . | Protein (mg/mL) . |
|---|---|---|---|---|
| rvWF | 104 | 8.0 | <0.001 | 0.86 |
| LMW-rvWF | 213 | 2.9 | <0.001 | 2.80 |
| pdvWF no. 2346641 | 73 | 45.0 | 25 | 6.80 |
| pdvWF no. 2956641 | 147 | 66.0 | 38 | 8.80 |
Von Willebrand factor antigen (vWF:Ag), ristocetin cofactor activity (RCoF), FVIII levels measured in the 2-stage assay, and total protein content of human recombinant von Willebrand factor (rvWF), a fraction of human rvWF containing only low molecular weight multimers (LMW-rvWF) and human plasma-derived vWF (pdvWF).