Hemodynamic Characteristics of Venules
| Genotype Donor Platelets . | Platelet Activation . | Genotype Recipient . | TNF-α Recipient . | Venular Size (μm) . | Centerline Velocity (mm/s) . | Shear Rate (s−1) . |
|---|---|---|---|---|---|---|
| +/+ | − | +/+ | + | 28.7 ± 1.9 | 2.98 ± 0.40 | 516 ± 46 |
| +/+ | − | P−/− | + | 32.2 ± 2.1 | 3.36 ± 0.69 | 521 ± 100 |
| +/+ | − | E−/− | + | 30.5 ± 2.1 | 3.16 ± 0.38 | 516 ± 46 |
| +/+ | − | P/E−/− | + | 30.6 ± 1.7 | 2.87 ± 0.28 | 482 ± 64 |
| P−/− | − | P−/− | + | 31.3 ± 1.7 | 3.44 ± 0.27 | 559 ± 56 |
| P−/− | − | P/E−/− | + | 34.6 ± 1.6 | 3.67 ± 0.29 | 590 ± 52 |
| FucT IV/VII−/− | − | P−/− | + | 30.4 ± 0.4 | 3.50 ± 0.37 | 567 ± 56 |
| FucT IV/VII−/− | − | P/E−/− | + | 31.2 ± 2.1 | 2.83 ± 0.28 | 479 ± 56 |
| +/+ | + | P/E−/− | + | 35.1 ± 1.9 | 3.10 ± 0.37 | 430 ± 48 |
| P−/− | + | P/E−/− | + | 32.3 ± 1.6 | 3.32 ± 0.52 | 553 ± 46 |
| +/+ | + | P/E−/− | − | 32.3 ± 1.6 | 3.48 ± 0.45 | 517 ± 75 |
| Genotype Donor Platelets . | Platelet Activation . | Genotype Recipient . | TNF-α Recipient . | Venular Size (μm) . | Centerline Velocity (mm/s) . | Shear Rate (s−1) . |
|---|---|---|---|---|---|---|
| +/+ | − | +/+ | + | 28.7 ± 1.9 | 2.98 ± 0.40 | 516 ± 46 |
| +/+ | − | P−/− | + | 32.2 ± 2.1 | 3.36 ± 0.69 | 521 ± 100 |
| +/+ | − | E−/− | + | 30.5 ± 2.1 | 3.16 ± 0.38 | 516 ± 46 |
| +/+ | − | P/E−/− | + | 30.6 ± 1.7 | 2.87 ± 0.28 | 482 ± 64 |
| P−/− | − | P−/− | + | 31.3 ± 1.7 | 3.44 ± 0.27 | 559 ± 56 |
| P−/− | − | P/E−/− | + | 34.6 ± 1.6 | 3.67 ± 0.29 | 590 ± 52 |
| FucT IV/VII−/− | − | P−/− | + | 30.4 ± 0.4 | 3.50 ± 0.37 | 567 ± 56 |
| FucT IV/VII−/− | − | P/E−/− | + | 31.2 ± 2.1 | 2.83 ± 0.28 | 479 ± 56 |
| +/+ | + | P/E−/− | + | 35.1 ± 1.9 | 3.10 ± 0.37 | 430 ± 48 |
| P−/− | + | P/E−/− | + | 32.3 ± 1.6 | 3.32 ± 0.52 | 553 ± 46 |
| +/+ | + | P/E−/− | − | 32.3 ± 1.6 | 3.48 ± 0.45 | 517 ± 75 |