Table 4.

Postremission Outcomes at 4 Years Among Children With and Without Down Syndrome

NDS Outcome %CI95N No DS Outcome%CI95P Value
Postremission*  
 RFS 87  86%  (58-97)  730  57%  (49-65) .0002 
 DFS  87  81%  (52-94)  730  56% (49-63) .0002  
Chemotherapy  64  89%  (38-99) 232  54%  (37-70) .0001  
Allogeneic BMT†  33%  (6-79)  153  71%  (61-80) .17  
Autologous BMT†  6  67%  (30-90)  199  56%  (48-64) .49  
NDS Outcome %CI95N No DS Outcome%CI95P Value
Postremission*  
 RFS 87  86%  (58-97)  730  57%  (49-65) .0002 
 DFS  87  81%  (52-94)  730  56% (49-63) .0002  
Chemotherapy  64  89%  (38-99) 232  54%  (37-70) .0001  
Allogeneic BMT†  33%  (6-79)  153  71%  (61-80) .17  
Autologous BMT†  6  67%  (30-90)  199  56%  (48-64) .49  

*Based on as-treated analysis; excluded are 331 not in remission and 28 event/censored before entry.

F4-151

Two-year DFS.

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