Table 1. Characteristics of Leukemic... | American Society of Hematology

Table 1.

Characteristics of Leukemic Mice

Mouse^-150 No.	Sex	Age at Diagnosis (mo)	Physical Appearance^-151	Macroscopic Tumor Sites	Hematologic Parameters			Pathological Findings	Clinical Diagnosis
Mouse^-150 No.	Sex	Age at Diagnosis (mo)	Physical Appearance^-151	Macroscopic Tumor Sites	WBC (×10³/μL)	Hb (g/dL)	Plt (×10⁴/μL)	Pathological Findings	Clinical Diagnosis
4-3	F	3.5	Dead	Thy, Spl, LN		ND		ND	ALL
4-5	F	4	Moribund	Thy, SPl, LN	30	14.0	50	Tissue infiltration	ALL
					(90% lymphoblasts)			of lymphoblasts
4-5-2	F	11.5	Moribund	Spl, LN	45	3.1	>400	Tissue infiltration	CML/BC
					(>90% granulocytes)			of granulocytes and blast cell cluster in lung
4-5-4	M	11	Dead	Spl, LN		ND		Tissue infiltration of granulocytes	CML
4-5-6	M	11.5	Healthy	ND	10	8.0	200	ND	CML
					(>90% granulocytes)
4-5-10	M	11.5	Moribund	Spl, LN	15	4.1	>400	Tissue infiltration	CML
					(>90% granulocytes)			of granulocytes
4-5-6-2	F	8	Healthy	ND	9.1	13.9	107	ND	CML
					(>80% granulocytes)
4-5-6-3	F	8	Healthy	ND	9.0	14.5	80	ND	CML s/o
					(>60% granulocytes)
4-5-6-6	M	8	Healthy	ND	9.4	13.6	113	ND	CML
					(>80% granulocytes)
4-5-6-7	M	8	Healthy	ND	10.3	11.9	131	ND	CML
					(>80% granulocytes)

Mouse^-150 No.	Sex	Age at Diagnosis (mo)	Physical Appearance^-151	Macroscopic Tumor Sites	Hematologic Parameters			Pathological Findings	Clinical Diagnosis
Mouse^-150 No.	Sex	Age at Diagnosis (mo)	Physical Appearance^-151	Macroscopic Tumor Sites	WBC (×10³/μL)	Hb (g/dL)	Plt (×10⁴/μL)	Pathological Findings	Clinical Diagnosis
4-3	F	3.5	Dead	Thy, Spl, LN		ND		ND	ALL
4-5	F	4	Moribund	Thy, SPl, LN	30	14.0	50	Tissue infiltration	ALL
					(90% lymphoblasts)			of lymphoblasts
4-5-2	F	11.5	Moribund	Spl, LN	45	3.1	>400	Tissue infiltration	CML/BC
					(>90% granulocytes)			of granulocytes and blast cell cluster in lung
4-5-4	M	11	Dead	Spl, LN		ND		Tissue infiltration of granulocytes	CML
4-5-6	M	11.5	Healthy	ND	10	8.0	200	ND	CML
					(>90% granulocytes)
4-5-10	M	11.5	Moribund	Spl, LN	15	4.1	>400	Tissue infiltration	CML
					(>90% granulocytes)			of granulocytes
4-5-6-2	F	8	Healthy	ND	9.1	13.9	107	ND	CML
					(>80% granulocytes)
4-5-6-3	F	8	Healthy	ND	9.0	14.5	80	ND	CML s/o
					(>60% granulocytes)
4-5-6-6	M	8	Healthy	ND	9.4	13.6	113	ND	CML
					(>80% granulocytes)
4-5-6-7	M	8	Healthy	ND	10.3	11.9	131	ND	CML
					(>80% granulocytes)

Abbreviations: Thy, thymus; Spl, spleen; LN, lymph node; ND, not done.

4-3 and 4-5 are founder mice. From 4-5-2 to 4-5-10 and from 4-5-6-2 to 4-5-6-7 are the first and second transgenic descendants of 4-5, respectively.

Status when diagnosed.