Table 2.

Expression of c-kit and Flt3 Receptors on Murine and Human Cell Lines

c-kitFlt3
Myeloid  Few positive  Mostly positive* 
Monocytic  Few  About 50%  
Erythroid  Most Few  
Megakaryocytic  Most  Few  
Mast cell  All None  
Lymphoid  
 Pro-B  None  Most  
 Pre-B None  Most* 
 B  None  Few  
 T  None  Few 
 Mature NK  ND  None  
Lymphomas  None  About 25% 
Myeloma  None  None 
c-kitFlt3
Myeloid  Few positive  Mostly positive* 
Monocytic  Few  About 50%  
Erythroid  Most Few  
Megakaryocytic  Most  Few  
Mast cell  All None  
Lymphoid  
 Pro-B  None  Most  
 Pre-B None  Most* 
 B  None  Few  
 T  None  Few 
 Mature NK  ND  None  
Lymphomas  None  About 25% 
Myeloma  None  None 

Results tabulated from a large number of reports. For individual references, see the sections of this report detailing the expression patterns for each of these receptors.

Abbreviation: ND, not determined.

*

Different expression patterns have been reported on mouse versus human cells; see text for details.

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