Data on Toxicities (SWOG ≥ Grade 2) of Dose-Intensive Melphalan and on Transfusion Support (n = 23)
Toxicity | Frequency % (n) |
Nausea/vomiting | 83 (19) |
Diarrhea | 65 (15) |
Mucositis | 91 (21) |
Pulmonary edema | 35 (8) |
Peripheral edema | 48 (11) |
Non-GI bleeding | 17 (4) |
GI bleeding | 22 (5) |
Hepatic | 13 (3) |
Renal | 35 (8) |
Metabolic | 35 (8) |
Sepsis | 26 (6) |
Transfusion component | Median (range) |
Units of red blood cells | 5 (0-14) |
Platelet transfusions | 6 (0-28) |
Toxicity | Frequency % (n) |
Nausea/vomiting | 83 (19) |
Diarrhea | 65 (15) |
Mucositis | 91 (21) |
Pulmonary edema | 35 (8) |
Peripheral edema | 48 (11) |
Non-GI bleeding | 17 (4) |
GI bleeding | 22 (5) |
Hepatic | 13 (3) |
Renal | 35 (8) |
Metabolic | 35 (8) |
Sepsis | 26 (6) |
Transfusion component | Median (range) |
Units of red blood cells | 5 (0-14) |
Platelet transfusions | 6 (0-28) |
Abbreviations: SWOG, Southwestern Oncology Group; GI, gastrointestinal.