Table 4.

Renal and Hepatic Responses

# Proteinuria (<150 mg/d) Alkaline Phosphatase (<120 U/L)Albumin (3.5-5.5 g/dL) Creatinine (<1.5 mg/dL)
Pre Post Pre Post Pre PostPre Post
A  6  11,370  1,573  124  108 2.3  4.0  1.0  0.9  
 7  12,800  11,400  104 77  2.2  2.5  1.0  4.1  
 11  9,234  8,293 90  64  2.2  2.3  0.7  0.9  
 13  9,653 7,320  135  111  2.1  3.1  0.8  0.9  
 22 6,030  421  146  194  1.7  2.7  0.9  1.2 
 23  16,390  21,625  59  61  1.2  1.7  0.9 7.1  
 24  16,400  7,560  96  80  1.9  3.7 1.1  1.3  
B  5  645  102  184  113  5.1 4.9  1.3  1.4  
 8  16,300  4,218  490  520 3.4  4.8  1.6  1.3  
 10  2,880  1,135 1,280  551  3.3  3.9  0.8  0.9  
 12 3,548 1,595  413  199  3.3  5.7  0.8  0.7 
 17  23,595 2,728  2,820  586  1.3  3.9 0.5  0.7  
C  14  3,542  992  362  278  4.0 5.1  1.5  1.7  
 18  2,420  4,189  1,488 160  2.7  3.3  0.9  1.3 
# Proteinuria (<150 mg/d) Alkaline Phosphatase (<120 U/L)Albumin (3.5-5.5 g/dL) Creatinine (<1.5 mg/dL)
Pre Post Pre Post Pre PostPre Post
A  6  11,370  1,573  124  108 2.3  4.0  1.0  0.9  
 7  12,800  11,400  104 77  2.2  2.5  1.0  4.1  
 11  9,234  8,293 90  64  2.2  2.3  0.7  0.9  
 13  9,653 7,320  135  111  2.1  3.1  0.8  0.9  
 22 6,030  421  146  194  1.7  2.7  0.9  1.2 
 23  16,390  21,625  59  61  1.2  1.7  0.9 7.1  
 24  16,400  7,560  96  80  1.9  3.7 1.1  1.3  
B  5  645  102  184  113  5.1 4.9  1.3  1.4  
 8  16,300  4,218  490  520 3.4  4.8  1.6  1.3  
 10  2,880  1,135 1,280  551  3.3  3.9  0.8  0.9  
 12 3,548 1,595  413  199  3.3  5.7  0.8  0.7 
 17  23,595 2,728  2,820  586  1.3  3.9 0.5  0.7  
C  14  3,542  992  362  278  4.0 5.1  1.5  1.7  
 18  2,420  4,189  1,488 160  2.7  3.3  0.9  1.3 

All of these patients had amyloid-related renal involvement, and patients in groups B and C had both renal and hepatic involvement. The patients in group A had predominant renal involvement, those in B predominant hepatic, and in C predominant cardiac involvement. The columns give pre- and post-therapy values for laboratory tests obtained for each patient, the post-therapy value being from the most recent follow-up. (Normal values)