Table 2.

Baseline Patient Characteristics, Amyloid Organ Involvement, and Responses to Therapy

Baseline Patient DataAmyloid Organ InvolvementSurvival and Responses
Patient Age/SexTime (mo)*Predominant Other Status (mo)Plasma Cell Disease Amyloid
1  41M  4  Hepatic Renal  Died, pretreatment  
2  42M  3  Neuropathic Cardiac  Alive, +38  CR  imp  
3  46M  5 Cardiac   Alive, +37  CR  imp  
4  39M  1 Neuropathic  Cardiac, lymphatic  Alive, +36  CR  imp 
5  45F  9  Hepatic  Renal  Alive, +34  CR  imp 
6  55F  18  Renal   Alive, +33  PD  imp  
7 53M  33  Renal   Alive, +31  PD  W  
8  42F 6  Hepatic  Cardiac, renal  Alive, +30  CR  imp 
9  45M  10  Neuropathic  Cardiac  Alive, +29  PD S  
10  56M  8  Hepatic  Renal, neuropathic  Died at +22  [CR]† [imp]† 
11  60M  8  Renal  Alive, +25  Relapse, +12  S  
12  55F  4 Hepatic  Renal  Alive, +23  CR  imp  
13  29F 4  Renal  Cardiac  Alive, +24  Relapse, +24  S 
14  58F  24  Cardiac  Renal, hepatic  Died at +20 [CR]† [imp]† 
15  53M  6  Cardiac  Renal Died at +5  [PD]† NA  
16  48M  1  Cardiac  Alive, +20  PD  S  
17  31F  3  Hepatic Cardiac, renal, neuropathic  Alive +19  CR  imp  
18 49F  2  Cardiac  Hepatic, renal, neuropathic  Alive +17 PD  imp  
19  40M  1  Cardiac  Renal, hepatic Died at +2  NA  NA  
20  57F  5  Lymphatic Cardiac, neuropathic  Died at +3  [PD]† [W]† 
21 39M  3  Cardiac  Neuropathic, hepatic  Died at +2 NA  NA  
22  56F  5  Renal  Cardiac  Alive, +14 CR  imp  
23  37F  4  Renal  Cardiac  Alive, +13  PD  W  
24  56M  5  Renal   Alive +12 Relapse, +12  imp  
25  48F  6  Cardiac  Renal, neuropathic  Died, pretreatment    
Baseline Patient DataAmyloid Organ InvolvementSurvival and Responses
Patient Age/SexTime (mo)*Predominant Other Status (mo)Plasma Cell Disease Amyloid
1  41M  4  Hepatic Renal  Died, pretreatment  
2  42M  3  Neuropathic Cardiac  Alive, +38  CR  imp  
3  46M  5 Cardiac   Alive, +37  CR  imp  
4  39M  1 Neuropathic  Cardiac, lymphatic  Alive, +36  CR  imp 
5  45F  9  Hepatic  Renal  Alive, +34  CR  imp 
6  55F  18  Renal   Alive, +33  PD  imp  
7 53M  33  Renal   Alive, +31  PD  W  
8  42F 6  Hepatic  Cardiac, renal  Alive, +30  CR  imp 
9  45M  10  Neuropathic  Cardiac  Alive, +29  PD S  
10  56M  8  Hepatic  Renal, neuropathic  Died at +22  [CR]† [imp]† 
11  60M  8  Renal  Alive, +25  Relapse, +12  S  
12  55F  4 Hepatic  Renal  Alive, +23  CR  imp  
13  29F 4  Renal  Cardiac  Alive, +24  Relapse, +24  S 
14  58F  24  Cardiac  Renal, hepatic  Died at +20 [CR]† [imp]† 
15  53M  6  Cardiac  Renal Died at +5  [PD]† NA  
16  48M  1  Cardiac  Alive, +20  PD  S  
17  31F  3  Hepatic Cardiac, renal, neuropathic  Alive +19  CR  imp  
18 49F  2  Cardiac  Hepatic, renal, neuropathic  Alive +17 PD  imp  
19  40M  1  Cardiac  Renal, hepatic Died at +2  NA  NA  
20  57F  5  Lymphatic Cardiac, neuropathic  Died at +3  [PD]† [W]† 
21 39M  3  Cardiac  Neuropathic, hepatic  Died at +2 NA  NA  
22  56F  5  Renal  Cardiac  Alive, +14 CR  imp  
23  37F  4  Renal  Cardiac  Alive, +13  PD  W  
24  56M  5  Renal   Alive +12 Relapse, +12  imp  
25  48F  6  Cardiac  Renal, neuropathic  Died, pretreatment    

Abbreviations: CR, complete hematologic response; imp, improved; PD, persistent disease; W, worsened; S, stable; NA, not applicable.

*

Time from diagnosis to treatment.

†

Brackets indicate last recorded data.

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