Table 2.

Specific Markers for Neutrophil Compartments

Granules Content Markers Membrane Markers
Azurophilic granules  Lysosomal enzymes, myeloperoxidase, M6P-glycoproteins CD63, CD68  
Specific granules  Lactoferrin  CD11b, cytochrome b  
Gelatinase granules  Gelatinase  CD11b, cytochrome b  
Other Compartments  
 Secretory vesicles Albumin  Alkaline phosphatase, CD35, CD11b, cytochrome b 
 Multivesicular bodies & multilaminar compartments M6P-glycoproteins  LAMP-2/LAMP-1  
 Plasma membrane   HLA-1 
Granules Content Markers Membrane Markers
Azurophilic granules  Lysosomal enzymes, myeloperoxidase, M6P-glycoproteins CD63, CD68  
Specific granules  Lactoferrin  CD11b, cytochrome b  
Gelatinase granules  Gelatinase  CD11b, cytochrome b  
Other Compartments  
 Secretory vesicles Albumin  Alkaline phosphatase, CD35, CD11b, cytochrome b 
 Multivesicular bodies & multilaminar compartments M6P-glycoproteins  LAMP-2/LAMP-1  
 Plasma membrane   HLA-1 

References are found in the text, except for CD35.65 

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