Correlation Between Bilirubin Levels Requiring Phototherapy (jaundice) and Length of TATAA Element in the Promoter Region of UGT1 Gene in a Population of Newborns Affected With HS
Length of TATAA Element in Promoter Region . | Jaundice . | Normal . |
---|---|---|
A(TA)7TAA/A(TA)7TAA | 29 (97%) | 1 (3%) |
A(TA)7TAA/A(TA)6TAA | 83 (56%) | 65 (44%) |
A(TA)6TAA/A(TA)6TAA | ||
Total | 112 (63%) | 66 (37%) |
Length of TATAA Element in Promoter Region . | Jaundice . | Normal . |
---|---|---|
A(TA)7TAA/A(TA)7TAA | 29 (97%) | 1 (3%) |
A(TA)7TAA/A(TA)6TAA | 83 (56%) | 65 (44%) |
A(TA)6TAA/A(TA)6TAA | ||
Total | 112 (63%) | 66 (37%) |
χ2 test was used to assess the difference in the distribution of the 6/6-6/7 and 7/7 genotypes between jaundiced and normal bilirubin levels in HS newborns, and it showed a value of 17.6 with P < .001.