Table 1.

Correlation Between Bilirubin Levels Requiring Phototherapy (jaundice) and Length of TATAA Element in the Promoter Region of UGT1 Gene in a Population of Newborns Affected With HS

Length of TATAA Element in Promoter Region JaundiceNormal
A(TA)7TAA/A(TA)7TAA 29 (97%)  1 (3%) 
A(TA)7TAA/A(TA)6TAA  83 (56%) 65 (44%)  
A(TA)6TAA/A(TA)6TAA 
Total  112 (63%)  66 (37%) 
Length of TATAA Element in Promoter Region JaundiceNormal
A(TA)7TAA/A(TA)7TAA 29 (97%)  1 (3%) 
A(TA)7TAA/A(TA)6TAA  83 (56%) 65 (44%)  
A(TA)6TAA/A(TA)6TAA 
Total  112 (63%)  66 (37%) 

χ2 test was used to assess the difference in the distribution of the 6/6-6/7 and 7/7 genotypes between jaundiced and normal bilirubin levels in HS newborns, and it showed a value of 17.6 with P < .001.

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