Table 1.

Comparison of Peripheral Blood Parameters, Bone Marrow Cellularity (BMC), and Multilineage Progenitors Between Transgenic and Nontransgenic Sl/Sld Mice

Mice BMCaCFU-MIXaRBCsWBCs
Sl/Sld 35.04 ± 1.6  5,249 ± 731  2,605 ± 252  8.25 ± 0.4 
Sl/Sld-MR 45.11 ± 2.8e 11,162 ± 5,249c 3,506 ± 277b 10.6 ± 0.8f 
Sl/Sld-S 39.06 ± 2.9  11,352 ± 1,713d 2,649 ± 279  10.38 ± 1.1  
Wt 68.22 ± 3.4    9,774 ± 998  7,949 ± 420 10.85 ± 0.9 
Mice BMCaCFU-MIXaRBCsWBCs
Sl/Sld 35.04 ± 1.6  5,249 ± 731  2,605 ± 252  8.25 ± 0.4 
Sl/Sld-MR 45.11 ± 2.8e 11,162 ± 5,249c 3,506 ± 277b 10.6 ± 0.8f 
Sl/Sld-S 39.06 ± 2.9  11,352 ± 1,713d 2,649 ± 279  10.38 ± 1.1  
Wt 68.22 ± 3.4    9,774 ± 998  7,949 ± 420 10.85 ± 0.9 

CFU-MIX, white and red cell counts were performed as described in methods. Results are expressed as mean ± SEM.aper 2 hind limbs; bP < .05 versus Sl/Sld; cP < .05 versus Sl/Sld; dP < .01 versus Sl/Sld; P = .01 versus Sl/Sld; fP = .058 versus Sl/Sld. A minimum of 8 mice were analyzed from each group. White and red blood cell counts are expressed as mean × 103/mm3. Bone marrow cellularity (BMC) is expressed as mean × 106 per 2 hind limbs.

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