Comparison of Peripheral Blood Parameters, Bone Marrow Cellularity (BMC), and Multilineage Progenitors Between Transgenic and Nontransgenic Sl/Sld Mice
Mice . | BMCa . | CFU-MIXa . | RBCs . | WBCs . |
---|---|---|---|---|
Sl/Sld | 35.04 ± 1.6 | 5,249 ± 731 | 2,605 ± 252 | 8.25 ± 0.4 |
Sl/Sld-MR | 45.11 ± 2.8e | 11,162 ± 5,249c | 3,506 ± 277b | 10.6 ± 0.8f |
Sl/Sld-S | 39.06 ± 2.9 | 11,352 ± 1,713d | 2,649 ± 279 | 10.38 ± 1.1 |
Wt | 68.22 ± 3.4 | 9,774 ± 998 | 7,949 ± 420 | 10.85 ± 0.9 |
Mice . | BMCa . | CFU-MIXa . | RBCs . | WBCs . |
---|---|---|---|---|
Sl/Sld | 35.04 ± 1.6 | 5,249 ± 731 | 2,605 ± 252 | 8.25 ± 0.4 |
Sl/Sld-MR | 45.11 ± 2.8e | 11,162 ± 5,249c | 3,506 ± 277b | 10.6 ± 0.8f |
Sl/Sld-S | 39.06 ± 2.9 | 11,352 ± 1,713d | 2,649 ± 279 | 10.38 ± 1.1 |
Wt | 68.22 ± 3.4 | 9,774 ± 998 | 7,949 ± 420 | 10.85 ± 0.9 |
CFU-MIX, white and red cell counts were performed as described in methods. Results are expressed as mean ± SEM.aper 2 hind limbs; bP < .05 versus Sl/Sld; cP < .05 versus Sl/Sld; dP < .01 versus Sl/Sld; P = .01 versus Sl/Sld; fP = .058 versus Sl/Sld. A minimum of 8 mice were analyzed from each group. White and red blood cell counts are expressed as mean × 103/mm3. Bone marrow cellularity (BMC) is expressed as mean × 106 per 2 hind limbs.