Comparison of Blood Parameters for HBD Mice in the NIH Colony and the Original Report
| . | Hct (%) . | MCV (fL) . | Hgb (g/dL) . | MCHC (%) . | Protoporphyrin . |
|---|---|---|---|---|---|
| C57BL6/J-hbd/hbd | 39.6 ± 1.7 | 34.3 ± 1.3 | 10.3 ± 0.7 | 26.0 ± 0.7 | 298.6 ± 25.2 (ZPP) |
| C57BL6/J-+hbd/+hbd | 46.8 ± 1.7 | 48.2 ± 1.3 | 15.4 ± 0.7 | 32.8 ± 0.9 | 43.6 ± 5.2 (ZPP) |
| AB/Jena-Halle-hbd/hbd | 37.0 | 43.3 | 10.7 | 28.9 | 611 (FEP) |
| C57BL6/J-+hbd/+hbd | 45.7 | 51.6 | 14.1 | 30.9 | 50 (FEP) |
| . | Hct (%) . | MCV (fL) . | Hgb (g/dL) . | MCHC (%) . | Protoporphyrin . |
|---|---|---|---|---|---|
| C57BL6/J-hbd/hbd | 39.6 ± 1.7 | 34.3 ± 1.3 | 10.3 ± 0.7 | 26.0 ± 0.7 | 298.6 ± 25.2 (ZPP) |
| C57BL6/J-+hbd/+hbd | 46.8 ± 1.7 | 48.2 ± 1.3 | 15.4 ± 0.7 | 32.8 ± 0.9 | 43.6 ± 5.2 (ZPP) |
| AB/Jena-Halle-hbd/hbd | 37.0 | 43.3 | 10.7 | 28.9 | 611 (FEP) |
| C57BL6/J-+hbd/+hbd | 45.7 | 51.6 | 14.1 | 30.9 | 50 (FEP) |
Data in rows 1 (n = 5) and 2 (n = 5) were derived from our colony at the NIH and represent the mean ± SE. Data from rows 3 (n = 8) and 4 (n = 14) are from the original report.2
Abbreviations: Hct, hematocrit; Hgb, hemoglobin concentration. For the protoporphyrin values, (ZPP) = zinc-protoporphyrin in μmol ZPP/mol heme and (FEP) = free-erythrocyte protoporphyrin.