Pretransplant Patient Characteristics
. | AML-1°CR (n = 31) . | AML-2°CR (n = 8) . |
---|---|---|
Age [yr] | ||
Median [range] | 36.7 [16.5-51.5] | 32.9 [14.8-54.8] |
14-19 | 1 | 1 |
20-29 | 7 | 2 |
30-39 | 13 | 3 |
≥40 | 10 | 2 |
FAB classification | ||
M0 | 1 | |
M1 | 5 | 1 |
M2 | 12 | 1 |
M3 | 1 | 3 |
M4 | 5 | 1 |
M5 | 4 | |
M6 | 1 | |
Unknown/indeterminate | 2 | 2 |
Karyotype | ||
Normal | 7 | |
t[8;21]-150 | 7 | 1 |
t[15;17]-150 | 1 | 3 |
inv[16]-150 | 1 | |
trisomy 8 | 4 | |
Other pseudodiploid | 2 | 1 |
Other hyperdiploid | 1 | |
Not available | 8 | 3 |
No. of induction courses to achieve CR | ||
1 | 23 | n/a |
2 | 8 | n/a |
No. of consolidation courses | ||
0 | 5 | n/a |
1 | 21 | n/a |
2 | 5 | n/a |
Elapsed months to BMT, median [range] | ||
From diagnosis | 3.9 [2.4-8.8] | n/a |
From CR | 2.3 [0.6-7.8] | n/a |
Duration of first CR, months, median [range] | n/a | 11.44 [1.87-109] |
. | AML-1°CR (n = 31) . | AML-2°CR (n = 8) . |
---|---|---|
Age [yr] | ||
Median [range] | 36.7 [16.5-51.5] | 32.9 [14.8-54.8] |
14-19 | 1 | 1 |
20-29 | 7 | 2 |
30-39 | 13 | 3 |
≥40 | 10 | 2 |
FAB classification | ||
M0 | 1 | |
M1 | 5 | 1 |
M2 | 12 | 1 |
M3 | 1 | 3 |
M4 | 5 | 1 |
M5 | 4 | |
M6 | 1 | |
Unknown/indeterminate | 2 | 2 |
Karyotype | ||
Normal | 7 | |
t[8;21]-150 | 7 | 1 |
t[15;17]-150 | 1 | 3 |
inv[16]-150 | 1 | |
trisomy 8 | 4 | |
Other pseudodiploid | 2 | 1 |
Other hyperdiploid | 1 | |
Not available | 8 | 3 |
No. of induction courses to achieve CR | ||
1 | 23 | n/a |
2 | 8 | n/a |
No. of consolidation courses | ||
0 | 5 | n/a |
1 | 21 | n/a |
2 | 5 | n/a |
Elapsed months to BMT, median [range] | ||
From diagnosis | 3.9 [2.4-8.8] | n/a |
From CR | 2.3 [0.6-7.8] | n/a |
Duration of first CR, months, median [range] | n/a | 11.44 [1.87-109] |
Abbreviation: n/a, not applicable.
Associated with favorable outcomes after chemotherapy alone.19