Table 4.

Response to CD4+ DLI

Dose Level (CD4+ cells/kg)CML Cytogenetic or Stable-Phase RelapseCML (accelerated or blast crisis)Multiple Myeloma (>50% decrease in paraprotein) ALL/AML NHL/CLL MDS
Cytogenetic Response Molecular Response
1 (0.3 × 108) 10/14  7/14  0/4  1/2  1/6  
2 (1.0 × 108)  1/1  1/1  0/1  2/2  0/1 
3 (1.5 × 108)  4/4  4/4   2/2 
Total  15/19  12/19  0/5  5/6  1/7 
Dose Level (CD4+ cells/kg)CML Cytogenetic or Stable-Phase RelapseCML (accelerated or blast crisis)Multiple Myeloma (>50% decrease in paraprotein) ALL/AML NHL/CLL MDS
Cytogenetic Response Molecular Response
1 (0.3 × 108) 10/14  7/14  0/4  1/2  1/6  
2 (1.0 × 108)  1/1  1/1  0/1  2/2  0/1 
3 (1.5 × 108)  4/4  4/4   2/2 
Total  15/19  12/19  0/5  5/6  1/7 
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